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Table 2 CCR5 promoter variant (wild type/deletion) allele and genotype frequencies in serologically MV positive and negative sheep

From: First survey on association of TMEM154 and CCR5 variants with serological maedi-visna status of sheep in German flocks

Breed subset

MV status

CCR5 allele frequency

(n chromosomes)

P value

CCR5 genotype frequency

P value

(n sheep)

(n sheep)

(n sheep)

(n sheep)

del

wt

del/del

del/wt, wt/wt

All (521)

Negative (206)

0.19 (77)

0.81 (335)

0.021

0.04 (8)

0.96 (198)

0.519

Positive (315)

0.13 (85)

0.87 (545)

0.03 (9)

0.97 (306)

TEX-x (337)

Negative (96)

0.14 (26)

0.86 (166)

0.177

0.02 (2)

0.98 (94)

0.321

Positive (241)

0.10 (49)

0.90 (433)

0.01 (2)

0.99 (239)

GBM (39)

Negative (35)

0.37 (26)

0.63 (44)

0.253

0.11 (4)

0.89 (31)

0.321

Positive (4)

0.63 (5)

0.37 (3)

0.25 (1)

0.75 (3)

MLS-x (125)

Negative (62)

0.17 (21)

0.83 (103)

0.135

0.02 (1)

0.98 (61)

0.114

Positive (63)

0.25 (31)

0.75 (95)

0.10 (6)

0.90 (57)

EFM–LAC (20)

Negative (13)

0.15 (4)

0.85 (22)

0.278

0.08 (1)

0.92 (12)

1.000

positive (7)

0.00 (0)

1.00 (14)

0.00 (0)

1.00 (7)

  1. del: deletion, wt: wild type, TEX-x: purebred and crossbred German Texel sheep, GBM: purebred German Blackheaded Mutton sheep, MLS-x: purebred and crossbred Merinoland sheep, EFM–LAC: East Friesian milk and Lacaune sheep and crosses of both breeds.