Skip to main content

Table 2 CCR5 promoter variant (wild type/deletion) allele and genotype frequencies in serologically MV positive and negative sheep

From: First survey on association of TMEM154 and CCR5 variants with serological maedi-visna status of sheep in German flocks

Breed subset MV status CCR5 allele frequency
(n chromosomes)
P value CCR5 genotype frequency P value
(n sheep) (n sheep) (n sheep) (n sheep)
del wt del/del del/wt, wt/wt
All (521) Negative (206) 0.19 (77) 0.81 (335) 0.021 0.04 (8) 0.96 (198) 0.519
Positive (315) 0.13 (85) 0.87 (545) 0.03 (9) 0.97 (306)
TEX-x (337) Negative (96) 0.14 (26) 0.86 (166) 0.177 0.02 (2) 0.98 (94) 0.321
Positive (241) 0.10 (49) 0.90 (433) 0.01 (2) 0.99 (239)
GBM (39) Negative (35) 0.37 (26) 0.63 (44) 0.253 0.11 (4) 0.89 (31) 0.321
Positive (4) 0.63 (5) 0.37 (3) 0.25 (1) 0.75 (3)
MLS-x (125) Negative (62) 0.17 (21) 0.83 (103) 0.135 0.02 (1) 0.98 (61) 0.114
Positive (63) 0.25 (31) 0.75 (95) 0.10 (6) 0.90 (57)
EFM–LAC (20) Negative (13) 0.15 (4) 0.85 (22) 0.278 0.08 (1) 0.92 (12) 1.000
positive (7) 0.00 (0) 1.00 (14) 0.00 (0) 1.00 (7)
  1. del: deletion, wt: wild type, TEX-x: purebred and crossbred German Texel sheep, GBM: purebred German Blackheaded Mutton sheep, MLS-x: purebred and crossbred Merinoland sheep, EFM–LAC: East Friesian milk and Lacaune sheep and crosses of both breeds.