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Table 1 TMEM154 E/K allele and genotype frequencies in serologically MV positive and negative sheep

From: First survey on association of TMEM154 and CCR5 variants with serological maedi-visna status of sheep in German flocks

Breed subset

MV status

TMEM154 allele frequency

(n chromosomes)

P value

TMEM154 genotype frequency

P value

(n sheep)

(n sheep)

(n sheep)

(n sheep)

K

E

KK

EK, EE

All (527)

Negative (206)

0.65 (268)

0.35 (144)

< 0.001

0.48 (100)

0.52 (106)

< 0.001

Positive (321)

0.36 (233)

0.64 (409)

0.15 (47)

0.85 (274)

TEX-x (341)

Negative (95)

0.48 (92)

0.52 (98)

< 0.001

0.30 (29)

0.70 (66)

< 0.001

Positive (246)

0.26 (130)

0.74 (362)

0.04 (9)

0.96 (237)

GBM (39)

Negative (35)

0.66 (46)

0.34 (24)

0.140

0.40 (14)

0.60 (21)

0.277

Positive (4)

0.37 (3)

0.63 (5)

0.00 (0)

1.00 (4)

MLS-x (125)

Negative (62)

0.85 (105)

0.15 (19)

0.067

0.74 (46)

0.26 (16)

0.067

Positive (63)

0.75 (95)

0.25 (31)

0.59 (37)

0.41 (26)

EFM–LAC (22)

Negative (14)

0.89 (25)

0.11 (3)

0.001

0.79 (11)

0.21 (3)

0.006

Positive (8)

0.31 (5)

0.69 (11)

0.13 (1)

0.87 (7)

  1. TEX-x: purebred and crossbred German Texel sheep, GBM: purebred German Blackheaded Mutton sheep, MLS-x: purebred and crossbred Merinoland sheep, EFM–LAC: East Friesian milk and Lacaune sheep and crosses of both breeds.