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Table 1 TMEM154 E/K allele and genotype frequencies in serologically MV positive and negative sheep

From: First survey on association of TMEM154 and CCR5 variants with serological maedi-visna status of sheep in German flocks

Breed subset MV status TMEM154 allele frequency
(n chromosomes)
P value TMEM154 genotype frequency P value
(n sheep) (n sheep) (n sheep) (n sheep)
K E KK EK, EE
All (527) Negative (206) 0.65 (268) 0.35 (144) < 0.001 0.48 (100) 0.52 (106) < 0.001
Positive (321) 0.36 (233) 0.64 (409) 0.15 (47) 0.85 (274)
TEX-x (341) Negative (95) 0.48 (92) 0.52 (98) < 0.001 0.30 (29) 0.70 (66) < 0.001
Positive (246) 0.26 (130) 0.74 (362) 0.04 (9) 0.96 (237)
GBM (39) Negative (35) 0.66 (46) 0.34 (24) 0.140 0.40 (14) 0.60 (21) 0.277
Positive (4) 0.37 (3) 0.63 (5) 0.00 (0) 1.00 (4)
MLS-x (125) Negative (62) 0.85 (105) 0.15 (19) 0.067 0.74 (46) 0.26 (16) 0.067
Positive (63) 0.75 (95) 0.25 (31) 0.59 (37) 0.41 (26)
EFM–LAC (22) Negative (14) 0.89 (25) 0.11 (3) 0.001 0.79 (11) 0.21 (3) 0.006
Positive (8) 0.31 (5) 0.69 (11) 0.13 (1) 0.87 (7)
  1. TEX-x: purebred and crossbred German Texel sheep, GBM: purebred German Blackheaded Mutton sheep, MLS-x: purebred and crossbred Merinoland sheep, EFM–LAC: East Friesian milk and Lacaune sheep and crosses of both breeds.