Figure 1

Initial PrP BSE accumulation in a follicle of the IPP. WAIT 12 (4 mpi); A initial accumulation characterised by a fine granular reaction pattern in the cytoplasm of individual tingible body macrophages (TBMs); B fine granular PrPBSE depositions in a TBM (arrow); immunohistochemistry, PrP mAb 6C2, bar 20 µm.