Figure 5
From: Crosstalk between H9N2 avian influenza virus and crypt-derived intestinal organoids
![Figure 5](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13567-017-0478-6/MediaObjects/13567_2017_478_Fig5_HTML.gif)
Invasion of H9N2 virus affects ISC and Wnt signaling pathways. A–D RT-qPCR analysis of the relative expression of marker genes in ISC (Lgr5, Bmi1) and Wnt signal pathway (wnt3 and Axin2) at 1, 12 and 48 h. E, F RT-qPCR determined relative mRNA expression of Notch pathway genes (Dll1 and Dll4). The results are representative of data from three independent experiments. Each data bar shown represents mean values ± SE of triplicate assays. *P < 0.05; **P < 0.01.