Figure 1

Paratuberculosis infection course and phenotypic traits of interest to reduce Map spread at herd scale: in bracket: the corresponding parameters coding for them in the model. Boxes, disease states; S, susceptible; R, no longer susceptible; T, transiently infectious; L, latent; Is, moderate shedder; Ic, high shedder or clinically affected animals. Green compartments: non infected states, orange compartments: infected states, dashed arrows: shedding, solid arrows: transitions between states, blue (large) arrows: changes in individual phenotypic traits that could limit Map spread at herd scale.