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Table 2 Comparison of the duration of pre-breeding to post-breeding antibody responses to C. burnetii in goats.

From: A longitudinal study of serological responses to Coxiella burnetii and shedding at kidding among intensively-managed goats supports early use of vaccines

Antibody type Type of immune response Time of occurrence Duration of antibody responses in weeks
n (rev) Mean Median (range) p value*
IgM phase 2 Primary Pre-breeding 57 (55) 10.9 5.5 (1.0, 51.0) 0.570
Post-breeding 7 (7) 5.9 6.0 (2.0, 12.0)  
Secondary Pre-breeding 24 (24) 10.4 9.0 (1.0, 34.0) 0.523
Post-breeding 18 (18) 8.4 4.0 (2.0, 33.0)  
IgG phase 2 Primary Pre-breeding 40 (27) 19.4 12.0 (1.0, 48.5) 0.376
Post-breeding 14 (5) 7.5 6.0 (2.5, 13.0)  
Secondary Pre-breeding 4 (3) 30.7 42.5 (3.0, 46.5) 0.564
Post-breeding 7 (2) 25.8 25.8 (17.0, 34.5)  
IgM phase 1 Primary Pre-breeding 29 (29) 5.1 4.0 (1.0, 12.0) 0.197
Post-breeding 9 (7) 2.9 3.0 (1.0, 6.0)  
Secondary Pre-breeding 3 (3) 1.3 1.0 (1.0, 2.0) 0.127
Post-breeding 4 (4) 2.9 3.5 (1.0, 3.5)  
IgG phase 1 Primary Pre-breeding 40 (12) 23.7 22.5 (5.0, 42.5) 0.897
Post-breeding 14 (14) 20.5 22.3 (5.0, 34.5)  
Secondary Pre-breeding 0 (0)
Post-breeding 1 (1) 11.5  
  1. Pre-breeding responses are those that started before the target breeding age while post-breeding responses are those that started after the target breeding age in intensively managed goats on the study farm in Victoria, Australia, 2014–2015
  2. rev. number of antibody responses that seroreverted (moved from positive to negative) which were used in calculating the duration of serological positivity, n total number of antibody responses
  3. * p values derived using the Mann–Whitney U test comparing the duration of pre-breeding immune responses to the post-breeding immune responses