Skip to main content

Table 5 Linear mixed regression coefficients and confidence intervals for all statistically significantly different comparisons between time points after inoculation with E. coli and baseline (0 h) for antimicrobial peptides

From: Oestrous cycle-dependent equine uterine immune response to induced infectious endometritis

Group

Gene

Time (h)

P value

Contrast

(95% CI)

Antimicrobial peptides

EBD1

3

<0.001

1185.8

(239.8, 5863)

12

<0.001

65950.5

(13 339, 326 071.6)

24

<0.001

7309.0

(1478.3, 36 137.1)

48

<0.001

580.3

(117.4, 2869.3)

72

<0.001

102.3

(20.7, 505.6)

Lysozyme

3

<0.001

41.5

(19.8, 87)

12

<0.001

23.6

(11.3, 49.4)

24

<0.001

40.1

(19.2, 84.1)

48

<0.001

19.4

(9.3, 40.7)

72

0.001

3.6

(1.7, 7.5)

SLPI

3

<0.001

510.8

(173.1, 1507.9)

12

<0.001

15,661.6

(5305.8, 46 229.3)

24

<0.001

1283.8

(434.9, 3789.6)

48

<0.001

408.6

(138.4, 1206)

72

<0.001

197.9

(67, 584.1)

LCN2

3

<0.001

9.4

(3.7, 23.8)

12

<0.001

71.6

(28.2, 182.2)

24

<0.001

64.4

(25.3, 163.8)

48

<0.001

20.4

(8, 51.9)

72

<0.001

19.3

(7.6, 49)

LFN

24

<0.001

6.3

(2.7, 15.1)

48

<0.001

8.1

(3.4, 19.4)

72

<0.001

14.7

(6.2, 34.9)

UFN

3

<0.001

7.2

(2.8, 18.6)

12

<0.001

9.2

(3.6, 23.7)

24

0.035

2.8

(1.1, 7.1)

72

0.014

3.3

(1.3, 8.4)

P19

12

0.006

0.2

(0, 0.6)

24

0.002

0.1

(0, 0.5)

48

<0.001

0.1

(0, 0.3)

72

<0.001

0.0

(0, 0.1)

  1. Contrasts represent back-transformed regression coefficients for multiplicative interpretation.
  2. Time, time point in hours (h) after inoculation of E. coli.
  3. CI: confidence interval.