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Figure 6 | Veterinary Research

Figure 6

From: Distinct functional enrichment of transcriptional signatures in pigs with high and low IFN-gamma responses after vaccination with a porcine reproductive and respiratory syndrome virus (PRRSV)

Figure 6

In silico analysis of the relationship between IFNG and target genes. Based upon the analysis of upstream regulators using IPA (see Table 3 and Additional file 4) the predicted relationship between targeted molecules and IFNG in the High responder (HR) and Low responder (LR) vaccinated groups are displayed. Ten and 40 predicted relationships were identified with IFNG and target genes in the HR and LR group, respectively. Red color denotes predicted relationships leading to activation. Blue arrows denote predicted relationship leading to inhibition. Orange color denotes inconsistencies with the state of downstream molecule. Grey color denotes effect not predicted. *Represents targeted molecules in common between LR and HR vaccinated groups.

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