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Table 1 Association of CD163 positive cells in the endometrium and placenta and PRRSV RNA concentration in fetal thymus

From: Relationships of CD163 and CD169 positive cell numbers in the endometrium and fetal placenta with type 2 PRRSV RNA concentration in fetal thymus

PRRS RNA concentration in fetal thymus counte Coefficient (SE) 95% CI P values
Continuous model (relationship of cell numbers to PRRSV concentration in fetal thymus)
 Numbers of CD163 positive cells per 1 mm2 of endometrium 0.004 (0.002)a 0.0009, 0.007 0.011
 Numbers of CD163 positive cells per 1 mm2 of fetal placenta −0.002 (0.001)b −0.003, −0.0006 0.005
Inflated (logit) modelf (relationship of cell numbers to likelihood of PRRSV concentration in fetal thymus being equal to zero (PRSV negative)
 Numbers of CD163 positive cells per 1 mm2 of endometrium −0.044 (0.012)c −0.067, −0.021 <0.001
 Numbers of CD163 positive cells per 1 mm2 of fetal placenta 0.006 (0.003)d 0.0004, 0.011 0.033
  1. Results of zero-inflated Poisson regression model.
  2. aFor each one unit increase in the numbers of CD163 positive cells/mm2 of endometrium, PRRSV RNA concentration in fetal thymus increases by 0.004 log10 copies/mg.
  3. bFor each one unit increase in the numbers of CD163 positive cells/mm2 of fetal placenta PRRSV RNA concentration in the fetal thymus decreases by 0.002 log10 copies/mg.
  4. cFor each one unit change in the numbers of CD163 positive cells/mm2 of endometrium the odds of PRRSV RNA concentration in fetal thymus being equal to 0 (zero) decreases 1.045 times (e−0.044).
  5. dFor each one unit change in the numbers of CD163 positive cells/mm2 of fetal placenta the odds of PRRSV RNA concentration in the fetal thymus being equal to 0 (zero) increases 1.006 times (e0.006).
  6. eBased on the distribution of data, a count model was used after categorizing PRRSV RNA concentration into nine 1 − log10 replicates, from 0 to 9 log10 copies/mg.
  7. fThe logit portion of the model predicts the odds of a fetus being negative (PRRSV RNA concentration = 0) from the population of fetuses from infected and negative control gilts.