Vaccination sequence effects on immunological response and tissue bacterial burden in paratuberculosis infection in a rabbit model

Table 1 Percentage of IFN-γ release index upon stimulation with PPD due to vaccination

	PPD	VSI^a	IVS^b	p value
S1	AV	54.56	0.00	0.172
	BO	60.97	0.00	0.139
	JO	64.66	0.00	0.296
S3	AV	94.21	62.68	0.969
	BO	0.00	1.27	0.111
	JO	62.09	54.59	0.925
S10	AV	100.00	100.00	0.404
	BO	100.00	100.00	0.431
	JO	33.21	0.00	0.0019^*

AV: Avian PPD, BO: bovine PPD, JO: johnin PPD, VSI: vaccinated before infection, IVS: vaccinated after infection, S1: IFN-γ release index first sampling. S3: IFN-γ release index third sampling, S10: IFN-γ release index tenth sampling.
* p < 0.05.
^aIndex percentage in relation to the infected control group (VSI-IC)/VSI.
^bIndex percentage in relation to the infected control group (IVS-IC)/IVS.

ISSN: 1297-9716