Figure 1

Working scheme of animal infections. Hamsters were split into eight groups including a control group of non-infected animals (Group H1), groups of hamsters infected with JPCM5 strain either by infective sand fly bites or by IP inoculation (Groups H2-H4) and hamsters infected with L. infantum isolates from the Madrid outbreak either by infective sand fly bites or by IP inoculation (Groups H5-H8).