Figure 5

Gilt and fetal level predictors of viral load in fetal thymus. Grey font (text box at bottom right) indicates variables included in the full model (P < 0.05 in unconditional analyses), but excluded from final models due to non-significance during stepwise, backwards elimination. Levels of IL12 in supernatants of PRRSV stimulated PBMC collected at 19 dpi (IL12_sup_PRRSV_19 dpi) and absolute numbers of myeloid cells over time (Myel cells AUC0-19) were negatively associated (green arrows) with viral load in fetal thymus. Preservation category (viable (VIA), meconium stained (MEC), decomposed (DEC), autolyzed (AUT)), viral load at the maternal-fetal interface (PRRS VL MF_interface), the number of adjacent dead fetuses (No. dead neighbors) and the number of adjacent PRRSV RNA positive fetuses (No. PRRSV RNA positive neighbors) were positively associated (red arrows) with thymic viral load. P-values and coefficients (β) are indicated for significant factors.