Figure 6

Mortality (A) and morbidity (B) of prime-vaccinated growing piglets intranasally challenged with the indicated S. suis strains. Growing piglets were infected with wild type strain 10 (wt), 10Δide _Ssuis (Δ) and 10Δide _Ssuis _homologue (Δ_h) 12 days after prime vaccination with a homologous S. suis serotype 2 bacterin. A piglet was determined as morbid in the case of elevated body temperature (≥40.2 °C) or specific clinical signs (signs of central nervous dysfunction or severe lameness). Statistical analysis of the Kaplan-Meier diagrams was conducted with the log-rank test (all p-values are shown below the diagrams).