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Figure 1 | Veterinary Research

Figure 1

From: Host-specific exposure and fatal neurologic disease in wild raptors from highly pathogenic avian influenza virus H5N1 during the 2006 outbreak in Germany

Figure 1

Histopathological changes and influenza virus antigen expression in tissues of selected H5N1-infected wild raptors. Tissue sections in the left column are stained with hematoxylin and eosin (HE). Serial tissue sections in the right column are stained for influenza virus antigen by immunohistochemistry (IHC). In the brain (F1) and coelomic ganglion (B4), there is neuronal necrosis and lymphoplasmacytic and histiocytic inflammation associated with antigen expression in neurons and glial cells (red-brown staining). In the heart (B2) and pancreas (F1), there is necrosis and lymphoplasmacytic and histiocytic inflammation associated with antigen expression in the cardiomyocytes (heart) and exocrine pancreatic cells (pancreas). In all selected tissues freeze-thawn artifacts and mild autolytic changes are visible.

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Veterinary Research

ISSN: 1297-9716