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Table 2 Differential expression of genes involved in key biological functions between HPAIV infected chicken and duck cells (detected by microarray)

From: Highly pathogenic avian influenza virus infection in chickens but not ducks is associated with elevated host immune and pro-inflammatory responses

Gene symbol Gene name Entrez Gene ID Chicken cells Duck cells
   H5N1-tyEng91 H5N1-tyTR05 H5N1-tyEng91 H5N1-tyTR05
    Fold change Regulation Fold change Regulation Fold change Regulation Fold change Regulation
Signal transduction          
PRKAR2A Protein kinase, cAMP-dependent, regulatory, type II, alpha 416062 2.27 up 4.59 down 3.96 down 5.86 down
IPO7 Importin 7 423046 - unchanged 2.21 down 4.83 up 2.99 down
GTPase inhibitor activity          
GPS1 G protein pathway suppressor 1 417382 2.86 down 3.01 down 2.21 up 3.2 up
Lipid metabolism, production of ROS          
ACOX1 Acyl-Coenzyme A oxidase 1, palmitoyl 417366 4.33 down 2.88 down - unchanged 3.24 up
Enzymes          
B4GALNT3 Beta-1,4-N-acetyl-galactosaminyl transferase 3 418150 2.07 down 1.33 up 2.58 up 2.08 up
DNPEP Aspartyl aminopeptidase 424200 2.38 up 1.3 up - unchanged 1.44 down
Catalytic activity (vit B6 metabolism)          
PSAT1 Phosphoserine aminotransferase 1 427263 4.38 down 3.9 down 11.44 up 11.69 up
Transcription factor          
RREB1 Ras responsive element binding protein 1 395920 3.41 down 2.26 down 2.73 up 7.31 up
Isoleucyl-tRNA aminoacylation          
IARS2 Isoleucyl-tRNA synthetase 2, mitochondrial 421346 17.58 down 22.92 down 14.52 up 38.82 up
Peptidolysis, IL-4 biosynthesis          
MMP28 Matrix metallopeptidase 28 417523 2.66 down 1.93 down 3.31 up 10.38 up