Bovine viral diarrhea virus antigen in cerebral endothelium of a persistently infected goat kid. A weak, non-viable goat kid was born to a goat experimentally infected with bovine viral diarrhea virus (BVDV) 2 PA131 at approximately 25 days of gestation. A diagnosis of persistent BVDV infection was made based on virus isolation and antigen detection in buffy coat cells and ear notch samples, respectively. At necropsy, BVDV was detected by virus isolation from tissues. BVDV antigen staining was present in various tissues, but most pronounced in nervous and thymic tissues.