Skip to main content

Table 2 Effect of Rabbit Hemorrhagic Disease virus (RHDV) infection on mRNA levels of genes related to autophagy

From: Autophagic response in the Rabbit Hemorrhagic Disease, an animal model of virally-induced fulminant hepatic failure

  Control 12 h 18 h 24 h 30 h 36 h
Beclin-1 100 ± 11 118 ± 8 203 ± 16* 253 ± 36* 105 ± 6 87 ± 7
UVRAG 100 ± 6 104 ± 8 227 ± 19* 131 ± 15 81 ± 9* 99 ± 5
Atg5 100 ± 5 125 ± 11* 163 ± 19* 139 ± 7* 87 ± 7 63 ± 5
Atg12 100 ± 9 173 ± 12* 296 ± 41* 177 ± 9* 104 ± 8 82 ± 7
Atg16L1 100 ± 10 106 ± 9 223 ± 6* 140 ± 12* 130 ± 7* 106 ± 10
p62/SQSTM1 100 ± 4 145 ± 6* 192 ± 8* 202 ± 8* 86 ± 6 69 ± 4*
BiP 100 ± 7 118 ± 17 177 ± 41* 304 ± 29* 241 ± 39* 184 ± 18*
CHOP 100 ± 8 169 ± 10* 211 ± 19* 540 ± 79* 158 ± 9* 161 ± 13*
GRP94 100 ± 4 80 ± 4* 163 ± 5* 412 ± 54* 314 ± 13* 226 ± 21*
  1. Levels of mRNA were analyzed by real-time PCR assays. Data, normalized against β-Actin, are presented as percentage change from the control group. Values are expressed as means±S.E.M (n = 6). *P<0.05, compared with Control.