Phylogenetic analysis of ENTV-1OVC. (A) Phylogenetic relationship analysis of the full-length ENTV-1 genome sequence from the experimentally induced nasal tumor (ENTV-1OVC) and all other full-length ENTV-1 genome sequences available on GenBank as well as genome sequences from the genetically related ENTV-2 and JSRV. Accession numbers are shown in brackets. The percentage of replicate trees in which the associated taxa clustered together in the bootstrap test (1000 replicates) is shown next to the branches. Phylogenetic analyses were conducted using MEGA5 and all positions containing gaps and missing data were eliminated from the dataset. (B) A schematic showing the location of nucleotide differences between ENTV-1OVC and the closely related ENTV-1NA9. Small arrows indicated nucleotide changes and large arrows demarcate regions of variability previously identified.