An outbreak of feline infectious peritonitis in a Taiwanese shelter: epidemiologic and molecular evidence for horizontal transmission of a novel type II feline coronavirus

Table 3 The characteristics of 3c genes of FCoV recovered from various specimens of FIP cats

Case no.	Genotype of FCoV											S gene crossover site	Integrity of the 3c gene^b
Case no.	*NOC*	*R/F*	U	*A/P*	*CSF*	Li	Lu	Ki	Br	Sp	*Int*	S gene crossover site	*R/F*	*A/P*	Li	Lu	Ki	Br	Sp
1				II								4250^a		intact
7	II	II		II		II	II	II	II	II		4250	intact		intact	intact	intact		intact
8	II	I				+	II	II	+	-	-
9	II	I		II		+	II		II	II	+	4250		G210*				G210*	G210*
10						+	+	II	II		II	4250					intact
11	II	II	II	II	+	II	II	II		+		4250				E47*
12	II	II		II	II	+	II	II		II	+	4250	G210*	G210*
13		I/II			+	+	+	II	II	+		4250						Q218*

NOC, nasal/oral/conjunctival swabs; R/F, rectal swabs or fecal samples; A/P, ascites or pleural effusions; CSF, cerebrospinal fluid; Li, liver; Lu, lung; Ki, kidney; Br, brain; Sp, spleen; Int, intestine.
+: FCoV positive but the type of virus cannot be determined.
-: FCoV negative.
^a: FCoV/NTU2/R/2003; GenBank: DQ160294.
^b: E47*, G210* and Q218*: truncated 3c proteins with premature stop codons at amino acids 47, 210 and 218 were found, respectively.

ISSN: 1297-9716