Tissues | Spleen | Head kidney | Pancreas | Heart | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Genes | Weeks | |||||||||||
2 | 4 | 8 | 2 | 4 | 8 | 2 | 4 | 8 | 2 | 4 | 8 | |
IFN-γ | 0.7 ± 0.2 | 2.4 ± 0.5* | 0.8 ± 0.1 | 3.0 ± 0.7* | 4.1 ± 1.1* | 0.8 ± 0.1 | 3.4 ± 0.7 | 7.2 ± 0.9* | 1.5 ± 0.4 | 1.1 ± 0.2 | 6.3 ± 3.0* | 89.3 ± 23.2* |
TNF-α | 0.5 ± 0.1 | 0.7 ± 0.1 | 1.4 ± 0.4 | 1.2 ± 0.3 | 1.0 ± 0.3 | 0.6 ± 0.2 | 1.3 ± 0.3 | 1.4 ± 0.2 | 1.2 ± 0.1 | 2.2 ± 0.9 | 2.5 ± 0.3* | 8.1 ± 1.5* |
IL-12 | 0.7 ± 0.1 | 1.6 ± 0.2 | 0.8 ± 0.2 | 0.8 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.1 | 2.2 ± 0.3 | 0.6 ± 0.1** | 1.7 ± 0.4 | 1.0 ± 0.3 | 0.9 ± 0.2 | 3.3 ± 0.7* |
IL-10 | 0.9 ± 0.1 | 7.5 ± 1.4* | 2.8 ± 0.5* | 10.0 ± 1.6* | 21.2 ± 4.1* | 4.7 ± 1.1* | 3.1 ± 0.6 | 23.9 ± 6.5* | 3.2 ± 0.8* | 1.1 ± 0.3 | 4.1 ± 1.5 | 37.3 ± 7.6* |
IL-8 | 1.5 ± 0.3 | 1.5 ± 0.6 | 3.0 ± 0.6* | 1.0 ± 0.4 | 2.3 ± 0.8 | 1.9 ± 0.5 | 1.3 ± 0.2 | 1.7 ± 0.2 | 1.4 ± 0.2 | 1.0 ± 0.1 | 1.7 ± 0.3 | 5.7 ± 1.2* |
CD3-ε | 0.9 ± 0.1 | 0.9 ± 0.1 | 0.7 ± 0.1 | 0.6 ± 0.1 | 1.6 ± 0.2 | 1.7 ± 0.4 | 1.5 ± 0.3 | 1.4 ± 0.1 | 1.7 ± 0.2* | 1.0 ± 0.2 | 1.3 ± 0.2 | 10.4 ± 1.9* |
CD4 | 0.7 ± 0.1 | 1.3 ± 0.1 | 1.1 ± 0.2 | 0.7 ± 0.1 | 0.9 ± 0.1 | 1.1 ± 0.1 | 1.2 ± 0.2 | 1.1 ± 0.2 | 1.9 ± 0.3* | 1.1 ± 0.5 | 2.5 ± 0.7 | 11.1 ± 1.8* |
CD8 | 1.2 ± 0.2 | 1.3 ± 0.3 | 1.2 ± 0.3 | 1.0 ± 0.3 | 0.5 ± 0.1** | 0.7 ± 0.1 | 0.4 ± 0.0** | 0.7 ± 0.1 | 2.1 ± 0.2* | 1.0 ± 0.2 | 0.8 ± 0.3 | 51.6 ± 9.7* |
TCR-α | 1.5 ± 0.2 | 1.0 ± 0.1 | 1.0 ± 0.2 | 0.8 ± 0.2 | 0.6 ± 0.1** | 0.7 ± 0.1 | 1.4 ± 0.1 | 1.4 ± 0.2 | 2.0 ± 0.3* | 0.5 ± 0.1 | 0.8 ± 0.2 | 16.4 ± 2.5* |
MHC I | 1.7 ± 0.2 | 3.1 ± 0.2* | 1.5 ± 0.2 | 1.7 ± 0.2* | 2.4 ± 0.2* | 1.5 ± 0.1* | 3.7 ± 0.7* | 1.4 ± 0.2 | 2.1 ± 0.2* | 1.5 ± 0.3 | 4.4 ± 0.5* | 8.2 ± 0.8* |
MHC II | 1.1 ± 0.1 | 1.6 ± 0.2 | 1.2 ± 0.2 | 0.9 ± 0.1 | 1.7 ± 0.2* | 1.4 ± 0.2 | 1.8 ± 0.3 | 1.4 ± 0.2 | 1.6 ± 0.3 | 0.5 ± 0.1** | 1.5 ± 0.3 | 5.1 ± 0.8* |