Lesion profiles of C57BL/6, VM and C57BL/6 × VM mice, following stabilisation of the agent through the VM line. In (a) examples of isolates displaying the ME7 LP are shown. In (b) and (c) examples of isolates displaying the 87V, and VLA-V1 LP, respectively, are shown. (*) indicates that the sample originated in study 2. Only clinically and histopathologically positive animals were included in the profile. Error bars indicate standard error of the mean.