(A) Inflammatory scores in brain tissues from all surviving C57BL/6 mice after Neospora caninum challenge. Four groups of mice (13 animals per group) were immunized with either Neospora lysate antigen (NLA) associated with Synadenium carinatum latex lectin (ScLL), or NLA alone (antigen control), or ScLL alone (lectin control), or PBS (infection control). Mice (10 animals per group) were challenged with 2x107 tachyzoites of the Nc-1 isolate at 60 days after immunization and histopathological changes were analyzed. Bars represent mean ± SEM. (B) Representative photomicrographs of histological assays in brain tissues from mice of the four groups: NLA + ScLL, NLA, ScLL and PBS. Asterisks (*) indicate mononucleated cell infiltrates and/or infiltrates in the meninges. Haemtoxylin and eosin staining. Bar scale: 50 μm.