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Table 7 Serum levels of IL-8 after challenge with PRRSV at 84 days after the initial inoculation

From: Characterization of homologous and heterologous adaptive immune responses in porcine reproductive and respiratory syndrome virus infection

  Corrected† IL-8 levels in serum (pg/mL)
N° responding pigs; Average ± standard deviation
Experiment 1
Group
Days post-challenge
  1* 2* 3 14
C1 + B 2/2a
270 ± 108
2/2a
424 ± 255
2/2a
440 ± 434
2/2a
470 ± 606
1/2
711 ± N.A.
A + A 0/4
N.A.
1/4
440 ± N.A.
2/4
272 ± 363
1/4
822 ± N.A.
1/4
124 ± N.A.
A + B 2/4
644 ± 479
3/4
194 ± 98
0/4
N.A.
0/4
N.A.
0/4
N.A.
Experiment 2
Group
Days post-challenge
  1 2 3 7 14¶
C2 + A 0/3b
N.A.
0/3b
N.A.
0/3b
N.A.
0/3b
N.A.
0/3
N.A.
B + B 3/4
249 ± 192
1/4
526 ± N.A.
2/4
212 ± 211
2/4
262 ± 247
3/4
297 ± 273
B + A 2/3
38 ± 2
1/3
667 ± N.A.
2/3
1088 ± 407
1/3
577 ± N.A
3/3
291 ± 117
  1. In order to account the pre-2nd challenge levels of a given cytokine, values (pg/mL) obtained with samples of day 0 (84 pi) (C1 + B:653 ± 66; A + A:796 ± 306; A + B:1062 ± 157; C2 + A:503 ± 133; B + B:187 ± 198; B + A:41.3 ± 0) were subtracted to the values obtained at days 1, 2, 3, 7 or 14, respectively for producing a corrected value (Corrected value for cytokine X = Concentration of cytokine X day n - Concentration of cytokine X day 0).
  2. N.A. not applicable. Symbols (* p = 0.05; p < 0.05) show days for which statistical differences were observed between groups of a given experiment with regards to the proportion of positive pigs. Letters indicate statistically significant differences for the proportion of responding pigs for similar groups when comparing between experiments; i.e. naïve pigs inoculated with 3267 (C1 + B) vs. naïve pigs inoculated with 3262 (C2 + A). In this case, a,b correspond to p ≤ 0.1.