Figure 10
From: What have we learned from brucellosis in the mouse model?
Antibiotic treatment and antibody response of B. melitensis 16 M infected mice. Blue, pink and white circles represent log10 CFU/spleen in the left ordinates axis of the figure. White and black squares represent ELISA values at the right ordinates axis of the figure. Notice that the antibody titers in mice treated with antibiotics remain high over the 34 week period of the assay, in spite of the disappearance of Brucella CFU from the spleen. Some of the animals treated only with doxycycline may still harbor bacteria after 34 week period (adapted from [158, 159], with permission).