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Table 1 Relative quantification of mRNA transcripts in abomasal lymph node

From: Relationship between susceptibility of Blackface sheep to Teladorsagia circumcincta infection and an inflammatory mucosal T cell response

 

Susceptible vs Control

Resistant vs Control

Susceptible vs Resistant

Gene

fold change*

± sd

P-value

fold change

± sd

P-value

fold change

± sd

P-value

IL2

1.58 ± 0.51

0.20

1.31 ± 0.66

0.60

1.32 ± 0.43

0.68

IL4

ND

 

ND

 

ND

 

IL6

2.30 ± 0.43

<0.01

1.25 ± 0.45

0.88

1.95 ± 0.36

<0.01

IL7R

1.04 ± 0.28

0.10

−1.01 ± 0.54

0.96

1.17 ± 0.31

0.98

IL10

1.73 ± 0.60

0.16

1.51 ± 0.29

0.42

1.16 ± 0.40

0.78

IL17A

ND

 

ND

 

ND

 

IL12B

−1.23 ± 0.25

0.74

1.15 ± 0.69

0.90

−1.25 ± 0.24

0.48

IL21

2.06 ± 0.78

0.03

−1.01 ± 0.48

0.99

2.24 ± 0.85

0.03

IL23A

1.40 ± 0.19

0.23

1.19 ± 0.36

0.76

1.22 ± 0.16

0.58

IL25

ND

 

ND

 

ND

 

EBI3

−2.56 ± 0.19

0.02

−1.19 ± 0.46

0.63

−1.85 ± 0.27

0.10

FOXP3

1.68 ± 0.33

0.04

1.91 ± 0.43

<0.01

−1.11 ± 0.18

0.59

IFNG

−1.66 ± 0.23

0.04

−1.22 ± 0.22

0.40

−1.32 ± 0.29

0.38

TGFB1

1.51 ± 0.28

0.22

1.46 ± 0.49

0.16

1.08 ± 0.20

0.98

  1. * Fold change is the ratio of normalized mean expression between groups. Means of the uninfected controls were used as the calibrator and compared with the infected animals; n = 5 for each group.
  2. ND; not determined, IL4, IL17A and IL25 levels were outside the dynamic range of linearity of the assay and were too low to be accurately quantified and therefore valid comparisons could not be made. Bold is P ≤ 0.05.
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Veterinary Research

ISSN: 1297-9716