Figure 1

Foot lesion scores in healthy and footrot-affected sheep treated with selenium or saline. Footrot-affected (FR) sheep receiving monthly Se injections, had A) lower foot lesion scores (overall: P = 0.04), and in particular at 3 (P = 0.07) and 6 (P = 0.03) months after the start of the study. B) After stratifying FR-affected sheep by whole-blood Se (WB-Se) status at 3 months after the start of the study (WB-Se cut-off: 250 ng/mL), sheep with WB-Se concentrations above 250 ng/mL (FR-High Se) had decreased foot lesion scores by the end of the study (P = 0.04), whereas foot lesion scores did not change (P = 0.68) in sheep with WB-Se concentrations below 250 ng/mL (FR-Low Se). As a result, foot lesion scores were lower in FR-High Se sheep compared with FR-Low Se sheep (overall P = 0.02).