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Figure 8 | Veterinary Research

Figure 8

From: Malignant catarrhal fever induced by Alcelaphine herpesvirus 1 is characterized by an expansion of activated CD3+CD8+CD4- T cells expressing a cytotoxic phenotype in both lymphoid and non-lymphoid tissues

Figure 8

Gene expression profile of CD8+ cells during WD-MCF in rabbits. (A) CD8+ cells were sorted to high purity (≥ 96%) and RNA extracted before analysis of expression levels of genes associated with T cells and cytotoxicity: CD8-beta chain (Cd8b), perforin (Prf1), FAS-ligand (Faslg), IFN-γ (Ifng), tumor necrosis factor-alpha (Tnf), interleukin 2 (Il2) and interleukin 10 (Il10). Relative expression levels normalized to 100 ng total RNA are shown. Data are representative of two independent experiments (n = 3). Bars show means ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, ns: not significant.

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Veterinary Research

ISSN: 1297-9716