Figure 1From: A trypsin-like serine protease is involved in pseudorabies virus invasion through the basement membrane barrier of porcine nasal respiratory mucosaPlaque latitude and penetration depth underneath the basement membrane (BM) of PRV(89V87) plaques at 20 h pi in mock-treated (white bars) and protease inhibitor-treated (marked bars) porcine nasal respiratory mucosa explants. Explants were treated with a broad-spectrum protease inhibitor cocktail (complete Mini), inhibiting serine, cysteine and metalloproteases, or with an aspartyl protease inhibitor, pepstatin A, at 1 h pi until sampling. Data are represented as means of 10 plaques of duplicate independent experiments + SD (error bars).Back to article page