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  1. Lawsonia intracellularis is the causative agent of proliferative enteropathy. While it harbors genes encoding the entire apparatus required for the type III secretion system (T3SS) and the expression of some of t...

    Authors: Cang Chen, Yimin Dai, Yingying Yang, Zihe Zhu, Qinghua Zhang, Xuejiao An and Fenju Lai
    Citation: Veterinary Research 2022 53:39
  2. Environmental transmission of Chlamydia abortus as a result of enzootic disease or disease outbreaks and the threats posed by this pathogen has been previously reported, however a state-of-the-science review of t...

    Authors: Lauretta Turin, Sara Surini, Nick Wheelhouse and Mara Silvia Rocchi
    Citation: Veterinary Research 2022 53:37
  3. Th9 cells have been shown to play crucial roles in anti-parasite immunity, pathogenic microbe infection, and allergy. Previous studies have demonstrated that Haemonchus contortus excretory and secretory proteins ...

    Authors: Meng Liang, Mingmin Lu, Muhammad Tahir Aleem, Yang Zhang, Mingyue Wang, Zhaohai Wen, Xiaokai Song, Lixin Xu, Xiangrui Li and Ruofeng Yan
    Citation: Veterinary Research 2022 53:36
  4. Infection with Salmonella Typhimurium (S. Typhimurium) is a common cause of food-borne zoonosis leading to acute gastroenteritis in humans and pigs, causing economic losses to producers and farmers, and generatin...

    Authors: Juber Herrera-Uribe, Sara Zaldívar-López, Carmen Aguilar, Carmen Entrenas-García, Rocío Bautista, M. Gonzalo Claros and Juan J. Garrido
    Citation: Veterinary Research 2022 53:35
  5. Duck Tembusu virus (DTMUV), a member of the family Flaviviridae and an economically important pathogen with a broad host range, leads to markedly decreased egg production. However, the molecular mechanism underly...

    Authors: Yuhong Pan, Xuedong Wu, Wenjun Cai, Anchun Cheng, Mingshu Wang, Shun Chen, Juan Huang, Qiao Yang, Ying Wu, Di Sun, Sai Mao, Dekang Zhu, Mafeng Liu, Xinxin Zhao, Shaqiu Zhang, Qun Gao…
    Citation: Veterinary Research 2022 53:34
  6. Autophagy has been demonstrated to play important roles in the infection and pathogenesis of many viruses. We previously found that porcine parvovirus (PPV) infection can induce autophagy in porcine placental ...

    Authors: Xiujuan Zhang, Peipei Ma, Ting Shao, Yingli Xiong, Qian Du, Songbiao Chen, Bichen Miao, Xuezhi Zhang, Xiaoya Wang, Yong Huang and Dewen Tong
    Citation: Veterinary Research 2022 53:33
  7. The NF-κB pathway is an essential signalling cascade in the defence against viral infections, including African swine fever virus (ASFV) infection. ASFV encodes more than 151 proteins via its own transcription...

    Authors: Huan Chen, Zhenzhong Wang, Xiaoyu Gao, Jiaxuan Lv, Yongxin Hu, Yong-Sam Jung, Shanyuan Zhu, Xiaodong Wu, Yingjuan Qian and Jianjun Dai
    Citation: Veterinary Research 2022 53:32
  8. Trained immunity is the capacity of innate immune cells to produce an improved response against a secondary infection after a previous unrelated infection. Salmonellosis represents a public health issue and af...

    Authors: Rita Vaz-Rodrigues, Elisa Ferreras-Colino, María Ugarte-Ruíz, Michele Pesciaroli, Jobin Thomas, Teresa García-Seco, Iker A. Sevilla, Marta Pérez-Sancho, Rafael Mateo, Lucas Domínguez, Christian Gortazar and María A. Risalde
    Citation: Veterinary Research 2022 53:31
  9. Avian pathogenic Escherichia coli (APEC) is a pathotype of extraintestinal pathogenic E. coli and one of the most serious infectious diseases of poultry. It not only causes great economic losses to the poultry in...

    Authors: Lei Yin, Baoyan Cheng, Jian Tu, Ying Shao, Xiangjun Song, Xiaocheng Pan and Kezong Qi
    Citation: Veterinary Research 2022 53:30
  10. Interferon regulatory factors (IRFs) play a key role in many aspects of immune response, and IRF1, IRF3, and IRF7 are positive regulators of IFN induction in mammals. However, IRF3, as the most critical regula...

    Authors: Zhenyu Lin, Jie Wang, Nian Zhang, Jianshu Yi, Zhaofei Wang, Jingjiao Ma, Hengan Wang, Yaxian Yan, Kun Qian, Jianhe Sun and Yuqiang Cheng
    Citation: Veterinary Research 2022 53:29
  11. In two “départements” in the South-West of France, bovine tuberculosis (bTB) outbreaks due to Mycobacterium bovis spoligotype SB0821 have been identified in cattle since 2002 and in wildlife since 2013. Using who...

    Authors: Hélène Duault, Lorraine Michelet, Maria-Laura Boschiroli, Benoit Durand and Laetitia Canini
    Citation: Veterinary Research 2022 53:28
  12. With a worldwide distribution, Eimeria spp. could result in serious economic losses to the poultry industry. Due to drug resistance and residues, there are no ideal drugs and vaccines against Eimeria spp. in food...

    Authors: ZhengQing Yu, SiYing Chen, JianMei Huang, WenXi Ding, YuFeng Chen, JunZhi Su, RuoFeng Yan, LiXin Xu, XiaoKai Song and XiangRui Li
    Citation: Veterinary Research 2022 53:27
  13. Mycoplasma hyorhinis may cause systemic inflammation of pigs, typically polyserositis and arthritis, and is also associated with several types of human cancer. However, the pathogenesis of M. hyorhinis colonizing...

    Authors: Jia Wang, Yanfei Yu, Yao Li, Shiyang Li, Li Wang, Yanna Wei, Yuzi Wu, Bala Pillay, Ademola Olufolahan Olaniran, Thamsanqa E. Chiliza, Guoqing Shao, Zhixin Feng and Qiyan Xiong
    Citation: Veterinary Research 2022 53:26
  14. Biomarkers of inflammation are valuable tools for health status evaluation in numerous species. However, in poultry, methods for measuring acute phase proteins (APP) are sparse and rely on manual laboratory la...

    Authors: Sofie Kromann, Rikke Heidemann Olsen, Anders Miki Bojesen, Henrik Elvang Jensen and Ida Thøfner
    Citation: Veterinary Research 2022 53:25
  15. Circular RNAs (circRNAs) are a new type of endogenous noncoding RNA that exhibit a variety of biological functions. However, it is not clear whether they are involved in foot-and-mouth disease virus (FMDV) inf...

    Authors: JinKe Yang, Bo Yang, Yong Wang, Ting Zhang, Yu Hao, HuiMei Cui, DengShuai Zhao, XingGuo Yuan, XueHui Chen, ChaoChao Shen, WenQian Yan, HaiXue Zheng, KeShan Zhang and Xiangtao Liu
    Citation: Veterinary Research 2022 53:24
  16. Streptococcus suis is a significant economic and welfare concern in the swine industry. Pan-genome analysis provides an in-silico approach for the discovery of genes involved in pathogenesis in bacterial pathogen...

    Authors: April A. Estrada, Marcelo Gottschalk, Connie J. Gebhart and Douglas G. Marthaler
    Citation: Veterinary Research 2022 53:23
  17. Retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) are cytosolic pattern recognition receptors that initiate innate antiviral immunity. Recent reports found that duck RLRs significantly restrict duck...

    Authors: Tianqiong He, Mingshu Wang, Anchun Cheng, Qiao Yang, Ying Wu, Renyong Jia, Shun Chen, Dekang Zhu, Mafeng Liu, Xinxin Zhao, Shaqiu Zhang, Juan Huang, Bin Tian, Xumin Ou, Sai Mao, Di Sun…
    Citation: Veterinary Research 2022 53:22
  18. The aim of this study was to investigate whether oral administration of Lactobacillus brevis 23017 (LB) alone and in combination with ellagic acid inhibits ChTLR15/ChNLRP3/ChIL-1β by activating the Nrf2/HO-1 path...

    Authors: Xuelian Yang, Xinghui Pan, Zhipeng Jia, Bingrong Bai, Wenjing Zhi, Hang Chen, Chunli Ma and Dexing Ma
    Citation: Veterinary Research 2022 53:21
  19. Mycoplasma (M.) hyopneumoniae interacts with the respiratory microbiota and facilitates colonization of other pathogens. The present study investigated the pulmonary and nasal microbiota of M. hyopneumoniae-infec...

    Authors: Karina Sonalio, Henrique M. S. Almeida, Marina L. Mechler-Dreibi, Gabriel Y. Storino, Freddy Haesebrouck, Dominiek Maes and Luís Guilherme de Oliveira
    Citation: Veterinary Research 2022 53:20
  20. The intestinal epithelium is the first natural barrier against Trichinella spiralis larval invasion, but the mechanism of larval invasion of the gut epithelium is not fully elucidated. The aim of this study was t...

    Authors: Yan Yan Song, Qi Qi Lu, Lu Lu Han, Shu Wei Yan, Xin Zhuo Zhang, Ruo Dan Liu, Shao Rong Long, Jing Cui and Zhong Quan Wang
    Citation: Veterinary Research 2022 53:19
  21. The accumulation of unfolded or misfolded proteins in the endoplasmic reticulum can cause an endoplasmic reticulum stress (ERS) response. If ERS continues or cannot be alleviated, it will cause the production ...

    Authors: Jingyun Xu, Zixuan Pang, Jinpeng Zhang, Shuang Xia, Ruibiao Wang, Yuheng Zhang, Jingbo Zhen, Xuewei Song, Lihao Lin, Feng Sun, Xinxin Xuan and Yixin Lu
    Citation: Veterinary Research 2022 53:18
  22. Pasteurella multocida infection frequently causes fowl cholera outbreaks, leading to huge economic losses to the poultry industry worldwide. This study developed a novel live attenuated P. multocida vaccine strai...

    Authors: Xinxin Zhao, Fuxiang Yang, Hui Shen, Yi Liao, Dekang Zhu, Mingshu Wang, Renyong Jia, Shun Chen, Mafeng Liu, Qiao Yang, Ying Wu, Shaqiu Zhang, Juan Huang, Xumin Ou, Sai Mao, Qun Gao…
    Citation: Veterinary Research 2022 53:17
  23. Brucella melitensis and Brucella ovis are gram-negative pathogens of sheep that cause severe economic losses and, although B. ovis is non-zoonotic, B. melitensis is the main cause of human brucellosis. B. meliten...

    Authors: Pilar M. Muñoz, Raquel Conde-Álvarez, Sara Andrés-Barranco, María-Jesús de Miguel, Amaia Zúñiga-Ripa, Beatriz Aragón-Aranda, Miriam Salvador-Bescós, Estrella Martínez-Gómez, Maite Iriarte, Montserrat Barberán, Nieves Vizcaíno, Ignacio Moriyón and José M. Blasco
    Citation: Veterinary Research 2022 53:16
  24. Three-dimensional (3D) intestinal enteroids are powerful in vitro models for studying intestinal biology. However, due to their closed structure direct access to the apical surface is impeded, limiting high-th...

    Authors: Kate M. Sutton, Brigid Orr, Jayne Hope, Stina R. Jensen and Lonneke Vervelde
    Citation: Veterinary Research 2022 53:15
  25. Infectious diseases in livestock are well-known to infect multiple hosts and persist through a combination of within- and between-host transmission pathways. Uncertainty remains about the epidemic dynamics of ...

    Authors: Nicolas C. Cardenas, Abagael L. Sykes, Francisco P. N. Lopes and Gustavo Machado
    Citation: Veterinary Research 2022 53:14
  26. Porcine reproductive and respiratory syndrome virus (PRRSV) infection during late gestation negatively affects fetal development. The objective of this study was to identify the fetal organs most severely impa...

    Authors: Margaret K. Mulligan, Jocelyn E. Kleiman, Andrew C. Caldemeyer, John C. S. Harding and J. Alex Pasternak
    Citation: Veterinary Research 2022 53:13
  27. Recent publications suggest PCV2 vaccine-induced protection is superior when the vaccine and challenge are closely matched. PCV2’s evolutionary rate, propensity for recombination, and genotype shifting, all pr...

    Authors: Meggan Bandrick, Monica Balasch, Andrea Heinz, Lucas Taylor, Vickie King, Jeri Toepfer and Dennis Foss
    Citation: Veterinary Research 2022 53:12
  28. In late 2015, an epizootic of Highly Pathogenic Avian Influenza (H5Nx) was registered in Southwestern France, including more than 70 outbreaks in commercial poultry flocks. Phylogenetic analyses suggested loca...

    Authors: Nicolas Gaide, Marie-Noëlle Lucas, Mattias Delpont, Guillaume Croville, Kim M. Bouwman, Andreas Papanikolaou, Roosmarijn van der Woude, Iwan A. Gagarinov, Geert-Jan Boons, Robert P. De Vries, Romain Volmer, Angélique Teillaud, Timothée Vergne, Céline Bleuart, Guillaume Le Loc’h, Maxence Delverdier…
    Citation: Veterinary Research 2022 53:11
  29. Cell death and inflammation are intimately linked during mastitis due to Staphylococcus aureus (S. aureus). Pyroptosis, a programmed necrosis triggered by gasdermin protein family, often occurs after inflammatory...

    Authors: Xiaozhou Wang, Mingchao Liu, Na Geng, Yongzhen Du, Zhaoming Li, Xin Gao, Bo Han, Jianzhu Liu and Yongxia Liu
    Citation: Veterinary Research 2022 53:10
  30. The zoonotic pathogen Salmonella enterica serotype Enteritidis (SE) causes severe disease in young chickens. Restriction on antibiotic use requires alternative SE control strategies such as nutritional solutions ...

    Authors: Nathalie Meijerink, Jean E. de Oliveira, Daphne A. van Haarlem, David M. Lamot, Francisca C. Velkers, Hauke Smidt, J. Arjan Stegeman, Victor P. M. G. Rutten and Christine A. Jansen
    Citation: Veterinary Research 2022 53:9
  31. Cystic Echinococcosis (CE), a zoonotic parasitic disease, is caused by the cestode Echinococcus granulosus sensu lato. CE inflicts severe damage in cattle, sheep, and human hosts worldwide. Fertile CE cysts are c...

    Authors: Ismael Pereira, Christian Hidalgo, Caroll Stoore, María Soledad Baquedano, Carolina Cabezas, Macarena Bastías, Aníbal Riveros, Claudio Meneses, Martín Cancela, Henrique Bunselmeyer Ferreira, Leonardo Sáenz and Rodolfo Paredes
    Citation: Veterinary Research 2022 53:8
  32. The type I interferon (IFN-I) signaling pathway is an important part of the innate immune response and plays a vital role in controlling and eliminating pathogens. African swine fever virus (ASFV) encodes vari...

    Authors: Kaidian Yang, Ying Xue, Hui Niu, Chunwei Shi, Mingyang Cheng, Jianzhong Wang, Boshi Zou, Junhong Wang, Tianming Niu, Meiying Bao, Wentao Yang, Dandan Zhao, Yanlong Jiang, Guilian Yang, Yan Zeng, Xin Cao…
    Citation: Veterinary Research 2022 53:7
  33. Dihydromyricetin (DHM), a flavonoid in vine tea, has many pharmacological activities, including anti-inflammatory and antibacterial effects. Lipopolysaccharide is the key inducer of inflammation in avian patho...

    Authors: Chenxi Shi, Jiaqi Wang, Ruichen Zhang, Muhammad Ishfaq, Ying Li, Ruihui Zhang, Chuanbiao Si, Rui Li, Changwen Li and Fangping Liu
    Citation: Veterinary Research 2022 53:6
  34. In recent years, Klebsiella pneumoniae (KP) has caused disease outbreaks in different animals, resulting in serious economic losses and biosafety concerns. Considering the broad antibiotic resistance of KP, vacci...

    Authors: Gaowei Hu, Xue Chen, Wenhui Chu, Zhe Ma, Yingjie Miao, Xi Luo and Yongqian Fu
    Citation: Veterinary Research 2022 53:5
  35. Bovine respiratory disease (BRD), as one of the most common and costly diseases in the beef cattle industry, has significant adverse impacts on global food security and the economic stability of the industry. ...

    Authors: Jianmin Chai, Sarah F. Capik, Beth Kegley, John T. Richeson, Jeremy G. Powell and Jiangchao Zhao
    Citation: Veterinary Research 2022 53:4
  36. Trueperella pyogenes (T. pyogenes) is an opportunistic pathogen associated with a variety of diseases in many domestic animals. Therapeutic treatment options for T. pyogenes infections are becoming limited due to...

    Authors: Yuru Guo, Chengcheng Huang, Hongyu Su, Zehui Zhang, Menghan Chen, Ruxia Wang, Dexian Zhang, Luyao Zhang and Mingchun Liu
    Citation: Veterinary Research 2022 53:3
  37. The current investigation aimed at characterizing the cause of multiple disease outbreaks in the same broiler production unit during a course of 18 months. The outbreaks had mortality rates of up to 22%. Escheric...

    Authors: Anders Miki Bojesen, Umran Ahmed, Hanne Skaarup and Carmen Espinosa-Gongora
    Citation: Veterinary Research 2022 53:2
  38. To understand the differences in immune responses between early feathering (EF) and late feathering (LF) chickens after infection with avian leukosis virus, subgroup J (ALV-J), we monitored the levels of prola...

    Authors: Guodong Mo, Bowen Hu, Qihong Zhang, Zhuohao Ruan, Wangyu Li, Jiaying Liang, Yizi Shen, Zhixin Mo, Zihao Zhang, Zhuyue Wu, Meiqing Shi and Xiquan Zhang
    Citation: Veterinary Research 2022 53:1
  39. Viruses have evolved multiple strategies to manipulate their host’s translational machinery for the synthesis of viral proteins. A common viral target is the alpha subunit of eukaryotic initiation factor 2 (eI...

    Authors: Ting Zhu, Xueli Jiang, Hangkuo Xin, Xiaohui Zheng, Xiaonuan Xue, Ji-Long Chen and Baomin Qi
    Citation: Veterinary Research 2021 52:148
  40. The fusion (F) and haemagglutinin-neuraminidase (HN) proteins of Newcastle disease virus (NDV) are viral entry proteins and are recognized as the major virulence determinants. Previously, a lentogenic NDV viru...

    Authors: Xi Chen, Yanqing Jia, Ning Wei, Chao Ye, Huafang Hao, Sa Xiao, Xinglong Wang, Haijin Liu and Zengqi Yang
    Citation: Veterinary Research 2021 52:147
  41. Gram-negative bacteria are known to subvert eukaryotic cell physiological mechanisms using a wide array of virulence factors, among which the type three-secretion system (T3SS) is often one of the most importa...

    Authors: Hadis Rahmatelahi, Mansour El-Matbouli and Simon Menanteau-Ledouble
    Citation: Veterinary Research 2021 52:146
  42. Streptococcus suis is a zoonotic pathogen of swine involved in arthritis, polyserositis, and meningitis. Colonization of piglets by S. suis is very common and occurs early in life. The clinical outcome of infecti...

    Authors: Carlos Neila-Ibáñez, Louise Brogaard, Lola Pailler-García, Jorge Martínez, Joaquim Segalés, Mariela Segura, Peter M. H. Heegaard and Virginia Aragon
    Citation: Veterinary Research 2021 52:145
  43. Emergence of bovine mastitis caused by Prototheca algae is the impetus to better understand these infections. Both P. bovis and P. ciferrii belong to Prototheca algae, but they differ in their pathogenicity to in...

    Authors: Wenpeng Zhao, Fumeng He, Herman W. Barkema, Siyu Xu, Jian Gao, Gang Liu, Zhaoju Deng, Muhammad Shahid, Yuxiang Shi, John P. Kastelic and Bo Han
    Citation: Veterinary Research 2021 52:144
  44. Haemonchus contortus is a parasitic nematode of ruminants which causes significant losses to many farmers worldwide. Since the drugs currently in use for the treatment of haemonchosis are losing their effectivene...

    Authors: Markéta Zajíčková, Lukáš Prchal, Martina Navrátilová, Nikola Vodvárková, Petra Matoušková, Ivan Vokřál, Linh Thuy Nguyen and Lenka Skálová
    Citation: Veterinary Research 2021 52:143
  45. The intestinal epithelium plays a variety of roles including providing an effective physical barrier and innate immune protection against infection. Two-dimensional models of the intestinal epithelium, 2D ente...

    Authors: Brigid Orr, Kate Sutton, Sonja Christian, Tessa Nash, Helle Niemann, Lone Lind Hansen, Mike J. McGrew, Stina Rikke Jensen and Lonneke Vervelde
    Citation: Veterinary Research 2021 52:142
  46. Chlamydia psittaci was considered the predominant chlamydial species in poultry until Chlamydia gallinacea was discovered in 2009. C. psittaci is a zoonotic obligate intracellular bacterium reported in more than ...

    Authors: Marloes Heijne, Jeanet van der Goot, Herma Buys, Annemieke Dinkla, Hendrik Jan Roest, Lucien van Keulen and Ad Koets
    Citation: Veterinary Research 2021 52:141
  47. QseC, a histidine sensor kinase of the QseBC two-component system, acts as a global regulator of bacterial stress resistance, biofilm formation, and virulence. The function of QseC in some bacteria is well und...

    Authors: Yang Yang, Pei Hu, Lixu Gao, Xiang Yuan, Philip R. Hardwidge, Tian Li, Pan Li, Fang He, Yuanyi Peng and Nengzhang Li
    Citation: Veterinary Research 2021 52:140
  48. Chicken immune responses to infectious bronchitis virus (IBV) vaccination can depend on route of administration, vaccine strain and bird age. Typically for layer chickens, IBV vaccinations are administered by ...

    Authors: Mohammed Al-Rasheed, Christopher Ball and Kannan Ganapathy
    Citation: Veterinary Research 2021 52:139
  49. In this study, we investigated the role of heat shock protein 70 (HSP70) in porcine epidemic diarrhoea virus (PEDV) replication. We found that PEDV infection induced strong HSP70 overexpression in the very ear...

    Authors: Jae-Yeon Park, Jihoon Ryu, Jung-Eun Park, Eui-Ju Hong and Hyun-Jin Shin
    Citation: Veterinary Research 2021 52:138

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