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  1. Domestic cats are commonly affected by viral pathogens that induce lengthy infections with fatal outcomes. Prevention of viral propagation is of primordial importance in shelters and catteries, where cats from...

    Authors: Céline Robert-Tissot, Vera L Rüegger, Valentino Cattori, Marina L Meli, Barbara Riond, Peter F Moore, Monika Engels, Marco Franchini, Regina Hofmann-Lehmann and Hans Lutz

    Citation: Veterinary Research 2012 43:60

    Content type: Research

    Published on:

  2. Leishmania major is the major cause of cutaneous leishmaniosis (CL) outside of the Americas. In the present study we have cloned six Leishmania genes (H2A, H2B, H3, H4, A2 and HSP70) into the eukaryotic expressio...

    Authors: Gustavo Domínguez-Bernal, Pilar Horcajo, José A Orden, Ricardo De La Fuente, Aldara Herrero-Gil, Lara Ordóñez-Gutiérrez and Javier Carrión

    Citation: Veterinary Research 2012 43:59

    Content type: Research

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  3. Effects of probiotic bacteria on viral infections have been described previously. Here, two groups of sows and their piglets were fed with or without feed supplementation of the probiotic bacterium Enterococcus f...

    Authors: Susanne Kreuzer, Patrycja Machnowska, Jens Aßmus, Matthias Sieber, Robert Pieper, Michael FG Schmidt, Gudrun A Brockmann, Lydia Scharek-Tedin and Reimar Johne

    Citation: Veterinary Research 2012 43:58

    Content type: Research

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  4. Haemophilus parasuis, a member of the family Pasteurellaceae, is a common inhabitant of the upper respiratory tract of healthy pigs and the etiological agent of Glässer’s disease. As other virulent Pasteurellacea...

    Authors: Mar Costa-Hurtado, Maria Ballester, Nuria Galofré-Milà, Ayub Darji and Virginia Aragon

    Citation: Veterinary Research 2012 43:57

    Content type: Research

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  5. Orally delivered DNA vaccines against duck enteritis virus (DEV) were developed using live attenuated Salmonella typhimurium (SL7207) as a carrier and Escherichia coli heat labile enterotoxin B subunit (LTB) as a...

    Authors: Xia Yu, Renyong Jia, Juan Huang, Bin Shu, Dekang Zhu, Qing Liu, Xinghong Gao, Meng Lin, Zhongqiong Yin, Mingshu Wang, Shun Chen, Yin Wang, Xiaoyue Chen and Anchun Cheng

    Citation: Veterinary Research 2012 43:56

    Content type: Research

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  6. It has long been established that the sheep Prnp genotype influences the susceptibility to scrapie, and some studies suggest that it can also determine several aspects of the disease phenotype. Other studies, how...

    Authors: Lorenzo González, Martin Jeffrey, Mark P Dagleish, Wilfred Goldmann, Sílvia Sisó, Samantha L Eaton, Stuart Martin, Jeanie Finlayson, Paula Stewart, Philip Steele, Yvonne Pang, Scott Hamilton, Hugh W Reid and Francesca Chianini

    Citation: Veterinary Research 2012 43:55

    Content type: Research

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  7. Mycobacterial lipids have long been known to modulate the function of a variety of cells of the innate immune system. Here, we report the extraction and characterisation of polar and apolar free lipids from Mycob...

    Authors: Chris Pirson, Gareth J Jones, Sabine Steinbach, Gurdyal S Besra and H Martin Vordermeier

    Citation: Veterinary Research 2012 43:54

    Content type: Research

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  8. Lawsonia intracellularis is the causative agent of proliferative enteropathy, an endemic disease in pigs and an emerging concern in horses. Enterocyte hyperplasia is a common lesion in every case but there are di...

    Authors: Fabio A Vannucci, Nicola Pusterla, Samantha M Mapes and Connie Gebhart

    Citation: Veterinary Research 2012 43:53

    Content type: Research

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  9. Foodborne salmonellosis is one of the most important bacterial zoonotic diseases worldwide. Salmonella Typhimurium is the serovar most frequently isolated from persistently infected slaughter pigs in Europe. Circ...

    Authors: Alexander Van Parys, Filip Boyen, Elin Verbrugghe, Bregje Leyman, Flahou Bram, Freddy Haesebrouck and Frank Pasmans

    Citation: Veterinary Research 2012 43:52

    Content type: Research

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  10. Protection of cattle from alcelaphine herpesvirus-1 (AlHV-1)-induced malignant catarrhal fever (MCF) has been described previously, using an attenuated virus vaccine in an unlicensed adjuvant. The vaccine was ...

    Authors: George C Russell, Julio Benavides, Dawn Grant, Helen Todd, David Deane, Ann Percival, Jackie Thomson, Maira Connelly and David M Haig

    Citation: Veterinary Research 2012 43:51

    Content type: Research

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  11. Molecular epidemiology has proven to be an essential tool in the control of classical swine fever (CSF) and its use has significantly increased during the past two decades. Phylogenetic analysis is a prerequis...

    Authors: Alexander Postel, Stefanie Schmeiser, Jennifer Bernau, Alexandra Meindl-Boehmer, Gediminas Pridotkas, Zuzana Dirbakova, Miroslav Mojzis and Paul Becher

    Citation: Veterinary Research 2012 43:50

    Content type: Research

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  12. Histophilus somni is a Gram-negative bacterium and member of the Pasteurellaceae that is responsible for respiratory disease and other systemic infections in cattle. One of the bacterium’s virulence factors is an...

    Authors: Shaadi F Elswaifi, William K Scarratt and Thomas J Inzana

    Citation: Veterinary Research 2012 43:49

    Content type: Research

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  13. Peste des petits ruminants virus (PPRV) causes high mortality in goats and sheep and the disease has shown a greatly increased geographic distribution over the last 15 years. It is responsible for serious soci...

    Authors: Qianqian Hu, Weiye Chen, Kehe Huang, Michael D Baron and Zhigao Bu

    Citation: Veterinary Research 2012 43:48

    Content type: Research

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  14. Porcine reproductive and respiratory syndrome virus (PRRSV) is an arterivirus that shows a restricted in vivo tropism for subsets of porcine macrophages, with alveolar macrophages being major target cells. The...

    Authors: Miet I De Baere, Hanne Van Gorp, Peter L Delputte and Hans J Nauwynck

    Citation: Veterinary Research 2012 43:47

    Content type: Research

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  15. The surface exposed capsid proteins, VP1, VP2 and VP3, of foot-and-mouth disease virus (FMDV) determine its antigenicity and the ability of the virus to interact with host-cell receptors. Hence, modification o...

    Authors: Louise Lohse, Terry Jackson, Anette Bøtner and Graham J Belsham

    Citation: Veterinary Research 2012 43:46

    Content type: Research

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  16. The immunoinhibitory receptor T cell immunoglobulin domain and mucin domain-3 (Tim-3) and its ligand, galectin-9 (Gal-9), are involved in the immune evasion mechanisms for several pathogens causing chronic inf...

    Authors: Tomohiro Okagawa, Satoru Konnai, Ryoyo Ikebuchi, Saori Suzuki, Tatsuya Shirai, Yuji Sunden, Misao Onuma, Shiro Murata and Kazuhiko Ohashi

    Citation: Veterinary Research 2012 43:45

    Content type: Research

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  17. In order to develop a novel, safe and immunogenic fowl typhoid (FT) vaccine candidate, a Salmonella Gallinarum ghost with controlled expression of the bacteriophage PhiX174 lysis gene E was constructed using pMMP...

    Authors: Atul A Chaudhari, Chetan V Jawale, Sam Woong Kim and John Hwa Lee

    Citation: Veterinary Research 2012 43:44

    Content type: Research

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  18. Thirty-one sheep naturally infected with small ruminant lentiviruses (SRLV) of known genotype (A or B), and clinically affected with neurological disease, pneumonia or arthritis were used to analyse mannose re...

    Authors: Helena Crespo, Paula Jauregui, Idoia Glaria, Leticia Sanjosé, Laura Polledo, Juan F García-Marín, Lluís Luján, Damián de Andrés, Beatriz Amorena and Ramsés Reina

    Citation: Veterinary Research 2012 43:43

    Content type: Short report

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  19. Staphylococcus aureus is one of the most important causal agents of bovine mastitis. Population studies on bovine Staphylococcus aureus isolates have identified considerable genetic heterogeneity among strains ca...

    Authors: Katharina Schlotter, Ralf Ehricht, Helmut Hotzel, Stefan Monecke, Martin Pfeffer and Karsten Donat

    Citation: Veterinary Research 2012 43:42

    Content type: Research

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  20. The feline infectious peritonitis virus (FIPV) is a member of the feline coronavirus family that causes FIP, which is incurable and fatal in cats. Cyclosporin A (CsA), an immunosuppressive agent that targets t...

    Authors: Yoshikazu Tanaka, Yuka Sato, Shuichi Osawa, Mai Inoue, Satoka Tanaka and Takashi Sasaki

    Citation: Veterinary Research 2012 43:41

    Content type: Research

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  21. Bluetongue virus (BTV) is a double stranded (ds) RNA virus (genus Orbivirus; family Reoviridae), which is considered capable of infecting all species of domestic and wild ruminants, although clinical signs are se...

    Authors: Karin E Darpel, Paul Monaghan, Jennifer Simpson, Simon J Anthony, Eva Veronesi, Harriet W Brooks, Heather Elliott, Joe Brownlie, Haru-Hisa Takamatsu, Philip S Mellor and Peter PC Mertens

    Citation: Veterinary Research 2012 43:40

    Content type: Research

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  22. Tachyzoite clones obtained from a single Toxoplasma gondii oocyst field sample were genotyped and characterized regarding mouse virulence. PCR-RFLP genotyping of tachyzoites initially isolated from interferon-γ-k...

    Authors: Daland C Herrmann, Andrea Bärwald, Aline Maksimov, Nikola Pantchev, Majda G Vrhovec, Franz J Conraths and Gereon Schares

    Citation: Veterinary Research 2012 43:39

    Content type: Research

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  23. The immune responses of pregnant cattle and their foetuses were examined following inoculation on day 70 of gestation either intravenously (iv) (group 1) or subcutaneously (sc) (group 2) with live NC1 strain t...

    Authors: Paul M Bartley, Stephen E Wright, Stephen W Maley, Colin N Macaldowie, Mintu Nath, Clare M Hamilton, Frank Katzer, David Buxton and Elisabeth A Innes

    Citation: Veterinary Research 2012 43:38

    Content type: Research

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  24. Classical Swine Fever (CSF) is considered an endemic disease in European wild boar populations. In view of the high economic impact of the introduction of the virus into domestic pig units, huge efforts are in...

    Authors: Martin Lange, Stephanie Kramer-Schadt and Hans-Hermann Thulke

    Citation: Veterinary Research 2012 43:37

    Content type: Research

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  25. Phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway, activated during influenza A virus infection, can promote viral replication via multiple mechanisms. Direct binding of NS1 protein to p85β subunit of...

    Authors: Weizhong Li, Gefei Wang, Heng Zhang, Yanqin Shen, Jianping Dai, Liqi Wu, Jianxiang Zhou, Zhiwu Jiang and Kangsheng Li

    Citation: Veterinary Research 2012 43:36

    Content type: Research

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  26. T-2 toxin is known to be one of the most toxic trichothecene mycotoxins. Exposure to T-2 toxin induces many hematologic and immunotoxic disorders and is involved in immuno-modulation of the innate immune respo...

    Authors: Julie Seeboth, Romain Solinhac, Isabelle P Oswald and Laurence Guzylack-Piriou

    Citation: Veterinary Research 2012 43:35

    Content type: Research

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  27. The relationship between stress and disease is thought to be unambiguous: chronic stress induces immunosuppression, which likely increases the risk of infection. However, this link has not been firmly establis...

    Authors: Jennifer C Owen, Ayaka Nakamura, Courtney AC Coon and Lynn B Martin

    Citation: Veterinary Research 2012 43:34

    Content type: Research

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  28. Classical swine fever virus (CSFV) C-strain “Riems” escape variants generated under selective antibody pressure with monoclonal antibodies and a peptide-specific antiserum in cell culture were investigated. Ca...

    Authors: Immanuel Leifer, Sandra Blome, Ulrike Blohm, Patricia König, Heike Küster, Bodo Lange and Martin Beer

    Citation: Veterinary Research 2012 43:33

    Content type: Research

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  29. Although aspergillosis is one of the most common diseases in captive birds, the pathogenesis of avian aspergillosis is poorly known. We studied the role of avian respiratory macrophages as a first line of defe...

    Authors: Lieven Van Waeyenberghe, Frank Pasmans, Katharina D’Herde, Richard Ducatelle, Herman Favoreel, Shao-Ji Li, Freddy Haesebrouck and An Martel

    Citation: Veterinary Research 2012 43:32

    Content type: Research

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  30. The Extradomain A from fibronectin (EDA) has an immunomodulatory role as fusion protein with viral and tumor antigens, but its effect when administered with bacteria has not been assessed. Here, we investigate...

    Authors: Beatriz San Román, Victoria Garrido, Pilar-María Muñoz, Laura Arribillaga, Begoña García, Ximena De Andrés, Virginia Zabaleta, Cristina Mansilla, Inmaculada Farrán, Iñigo Lasa, Damián De Andrés, Beatriz Amorena, Juan-José Lasarte and María-Jesús Grilló

    Citation: Veterinary Research 2012 43:31

    Content type: Research

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  31. The present study characterized the homologous and heterologous immune response in type-I porcine reproductive and respiratory syndrome virus (PRRSV) infection. Two experiments were conducted: in experiment 1,...

    Authors: Ivan Díaz, Mariona Gimeno, Laila Darwich, Nuria Navarro, Liudmila Kuzemtseva, Sergio López, Ivan Galindo, Joaquim Segalés, Margarita Martín, Joan Pujols and Enric Mateu

    Citation: Veterinary Research 2012 43:30

    Content type: Research

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  32. Brucellosis is a zoonosis caused by Brucella species. Brucellosis research in natural hosts is often precluded by practical, economical and ethical reasons and mice are widely used. However, mice are not natur...

    Authors: María-Jesús Grilló, José María Blasco, Jean Pierre Gorvel, Ignacio Moriyón and Edgardo Moreno

    Citation: Veterinary Research 2012 43:29

    Content type: Review

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  33. This study assessed the presence of sialic acid α-2,3 and α-2,6 linked glycan receptors in seven avian species. The respiratory and intestinal tracts of the chicken, common quail, red-legged partridge, turkey,...

    Authors: Taiana Costa, Aida J Chaves, Rosa Valle, Ayub Darji, Debby van Riel, Thijs Kuiken, Natàlia Majó and Antonio Ramis

    Citation: Veterinary Research 2012 43:28

    Content type: Research

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  34. Aquaculture is the fastest growing food production sector in the world. However, the increased production has been accompanied by the emergence of infectious diseases. Heart and skeletal muscle inflammation (H...

    Authors: Øystein Wessel Finstad, Knut Falk, Marie Løvoll, Øystein Evensen and Espen Rimstad

    Citation: Veterinary Research 2012 43:27

    Content type: Research

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  35. Teladorsagia circumcincta is the most economically important gastrointestinal (abomasal) nematode parasite of sheep in cool temperate regions, to which sheep show genetically-varying resistance to infection. Lamb...

    Authors: Anton G Gossner, Virginia M Venturina, Darren J Shaw, Josephine M Pemberton and John Hopkins

    Citation: Veterinary Research 2012 43:26

    Content type: Research

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  36. Mycobacterium avium subspecies paratuberculosis is the causative agent of Johne’s disease, an intestinal disease of ruminants with major economic consequences. Infectious bacilli are phagocytosed by host macropha...

    Authors: David E MacHugh, Maria Taraktsoglou, Kate E Killick, Nicolas C Nalpas, John A Browne, Stephen DE Park, Karsten Hokamp, Eamonn Gormley and David A Magee

    Citation: Veterinary Research 2012 43:25

    Content type: Research

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  37. In order to assess the dynamics of influenza virus infection in pigs, serological and virological follow-ups were conducted in two whole batches of pigs from two different farms (F1 and F2), from 3 weeks of ag...

    Authors: Meritxell Simon-Grifé, Gerard E Martín-Valls, María J Vilar, Núria Busquets, Mercedes Mora-Salvatierra, Theo M Bestebroer, Ron AM Fouchier, Margarita Martín, Enric Mateu and Jordi Casal

    Citation: Veterinary Research 2012 43:24

    Content type: Research

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  38. Intestinal immune regulation including development of oral tolerance is of great importance for the maintenance of intestinal homeostasis. Concerning this, regulatory T cells (Tregs) occupy a pivotal role in c...

    Authors: Johannes Junginger, Ulrike Schwittlick, Frederik Lemensieck, Ingo Nolte and Marion Hewicker-Trautwein

    Citation: Veterinary Research 2012 43:23

    Content type: Research

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  39. The mycotoxin T-2 toxin and Salmonella Typhimurium infections pose a significant threat to human and animal health. Interactions between both agents may result in a different outcome of the infection. Therefore, ...

    Authors: Elin Verbrugghe, Virginie Vandenbroucke, Maarten Dhaenens, Neil Shearer, Joline Goossens, Sarah De Saeger, Mia Eeckhout, Katharina D'Herde, Arthur Thompson, Dieter Deforce, Filip Boyen, Bregje Leyman, Alexander Van Parys, Patrick De Backer, Freddy Haesebrouck, Siska Croubels…

    Citation: Veterinary Research 2012 43:22

    Content type: Research

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  40. A variety of mechanisms contribute to the viral-bacterial synergy which results in fatal secondary bacterial respiratory infections. Epidemiological investigations have implicated physical and psychological st...

    Authors: Paul D Hodgson, Palok Aich, Joseph Stookey, Yurij Popowych, Andrew Potter, Lorne Babiuk and Philip J Griebel

    Citation: Veterinary Research 2012 43:21

    Content type: Research

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  41. Staphylococcus aureus is an important cause of nosocomial and community-acquired infections in humans and animals, as well as the cause of mastitis in dairy cattle. Vaccines aimed at preventing S. aureus infectio...

    Authors: Liben Chen, Shuang Li, Zhengfang Wang, Ruilong Chang, Jingliang Su and Bo Han

    Citation: Veterinary Research 2012 43:20

    Content type: Research

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  42. The presence of foreign cells within the tissue/circulation of an individual is described as microchimerism. The main purpose of the present investigation was to study if microchimerism occurs in healthy sows/...

    Authors: Uladzimir U Karniychuk, Wander Van Breedam, Nadine Van Roy, Claire Rogel-Gaillard and Hans J Nauwynck

    Citation: Veterinary Research 2012 43:19

    Content type: Short report

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  43. Bovine mastitis remains the most common and costly disease of dairy cattle worldwide. A complementary control measure to herd hygiene and vaccine development would be to selectively breed cattle with greater r...

    Authors: Christopher D Russell, Stephanie Widdison, James A Leigh and Tracey J Coffey

    Citation: Veterinary Research 2012 43:17

    Content type: Research

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  44. West Nile virus (WNV) is a positive-stranded RNA virus belonging to the Flaviviridae family, a large family with 3 main genera (flavivirus, hepacivirus and pestivirus). Among these viruses, there are several g...

    Authors: Marina De Filette, Sebastian Ulbert, Michael S Diamond and Niek N Sanders

    Citation: Veterinary Research 2012 43:16

    Content type: Review

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  45. Numerous mammal species, including domestic and wild animals such as ruminants, dogs, cats and rodents, as well as humans, serve as reservoir hosts for various Bartonella species. Some of those species that explo...

    Authors: Hongkuan Deng, Danielle Le Rhun, Jean-Philippe R Buffet, Violaine Cotté, Amanda Read, Richard J Birtles and Muriel Vayssier-Taussat

    Citation: Veterinary Research 2012 43:15

    Content type: Review

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  46. Escherichia coli is a frequent cause of clinical mastitis in dairy cows. It has been shown that a prompt response of the mammary gland after E. coli entry into the lumen of the gland is required to control the in...

    Authors: Adeline Porcherie, Patricia Cunha, Angelina Trotereau, Perrine Roussel, Florence B Gilbert, Pascal Rainard and Pierre Germon

    Citation: Veterinary Research 2012 43:14

    Content type: Research

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  47. An enteroaggregative Verotoxin (Vtx)-producing Escherichia coli strain of serotype O104:H4 has recently been associated with an outbreak of haemolytic-uremic syndrome and bloody diarrhoea in humans mainly in Germ...

    Authors: Denis Piérard, Henri De Greve, Freddy Haesebrouck and Jacques Mainil

    Citation: Veterinary Research 2012 43:13

    Content type: Review

    Published on:

  48. Rabbit haemorrhagic disease virus (RHDV) is a calicivirus of the genus Lagovirus that causes rabbit haemorrhagic disease (RHD) in adult European rabbits (Oryctolagus cuniculus). First described in China in 1984, ...

    Authors: Joana Abrantes, Wessel van der Loo, Jacques Le Pendu and Pedro J Esteves

    Citation: Veterinary Research 2012 43:12

    Content type: Review

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  49. Endemic diseases of cattle, such as bovine viral diarrhea, have significant impact on production efficiency of food of animal origin with consequences for animal welfare and climate change reduction targets. M...

    Authors: Mark Tinsley, Fraser I Lewis and Franz Brülisauer

    Citation: Veterinary Research 2012 43:11

    Content type: Research

    Published on:

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