Figure 11
Expression pattern of TMPRSS2 in small and large intestines. D = duodenum, MJ = mid-jejunum, I = ileum, C = colon. A The expression of TMPRSS2 (green, FITC) was expressed as number of positive epithelial cells on the total number of epithelial cells. B The percentage of TMPRSS2+ cells in each villus (top and bottom) and crypt (small intestine) and three parts of each crypt (top 1/3rd, middle 1/3rd and bottom 1/3rd) (colon) was measured. Individual mean values ± SD of three pigs per age group were plotted according to intestinal region and age. Significant differences between the different age groups (two-way ANOVA with pairwise comparisons) are presented as *p < 0.05, **p < 0.01 or ***p ≤ 0.001. Scale bar: 125 µm and 25 µm.