Figure 1

Alpha diversity comparisons between IAV and control groups. IAV had significantly different Shannon diversity on days 3 (*) and 7 (**) relative to control (A), and significant differences in Inverse Simpson diversity relative to control were observed on days 1 (*) and 3 (*) (B). Each panel, from left to right, top to bottom refer to day 0 through day 42. The groups are indicated in the legend on the right: IAV (influenza A virus) = blue, and control = red. Box and whisker plots indicate the interquartile range (IQR) and 1.5 times the IQR. Outliers (higher or lower than 1.5 times the IQR) are indicated by black circles. Pairwise comparisons within groups across time and between groups at each time point were performed using the Wilcoxon rank sum test at a significance level of 0.05 (p < 0.05:*; p < 0.005:**).