A protein-based subunit vaccine with biological adjuvants provides effective protection against Pasteurella multocida in pigs

Table 3 Clinical and pathological analysis of pigs after challenge with P. multocida serotype A

Group	Total score^†	The score of gross lesions			Body weight (kg)
Group	Total score^†	Turbinate	Nasal septum	Lung	Total gain/11 days	Before challenge	After challenge
CpG (4)	15^ab	6	3	6	3.3 ± 1.2^a	19.1 ± 2.0	22.4 ± 1.6
w/o/w (4)	12^a	5	2	5	3.8 ± 0.7^a	17.9 ± 0.6	21.7 ± 0.7
Control (3)^*	19^b	6	4	9	2.6 ± 2.2^a	16.0 ± 2.8	18.6 ± 2.4

^*One of four pigs in the control group was sacrificed due to serious illness 2 days post challenge, so it was not included in the score.
^†Differences between groups compared to the controls using Duncan’s multiple comparison. A p value of < 0.05 was considered significant.

ISSN: 1297-9716