Table 2 GO term enrichment annotations for ED18 enteroid network clusters grouped into similar time-point expression profiles.
Cluster | GO term no | Significantly-enriched GO term (p < 0.05) | p value | Genes in gene set | Genes in cluster | Genes in overlap | % overlap |
|---|---|---|---|---|---|---|---|
High 1Â day | |||||||
 3 | 6091 | GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | 9.68E-59 | 532 | 704 | 81 | 15.22556 |
 3 | 46034 | ATP_METABOLIC_PROCESS | 9.19E-56 | 303 | 704 | 64 | 21.12211 |
 3 | 7005 | MITOCHONDRIAL_ORGANIZATION | 4.17E-71 | 528 | 704 | 91 | 17.23485 |
 19 | 98798 | MITOCHONDRIAL_PROTEIN_COMPLEX | 2.19E-08 | 260 | 69 | 7 | 2.692308 |
 19 | 16071 | MRNA_METABOLIC_PROCESS | 2.65E-09 | 840 | 69 | 11 | 1.309524 |
High 1–7 day | |||||||
 9 | 46903 | SECRETION | 1.32E-08 | 1680 | 179 | 24 | 1.428571 |
 9 | 5773 | VACUOLE | 7.76E-10 | 781 | 179 | 18 | 2.304738 |
 9 | 44257 | CELLULAR_PROTEIN_CATABOLIC_PROCESS | 5.64E-09 | 782 | 179 | 17 | 2.173913 |
 11 | 70727 | CELLULAR_MACROMOLECULE_LOCALIZATION | 2.49E-07 | 1930 | 143 | 20 | 1.036269 |
 11 | 6508 | PROTEOLYSIS | 6.74E-08 | 1779 | 143 | 20 | 1.124227 |
 13 | 44255 | CELLULAR_LIPID_METABOLIC_PROCESS | 2.80E-07 | 1064 | 109 | 14 | 1.315789 |
 13 | 16050 | VESICLE_ORGANIZATION | 2.97E-11 | 330 | 109 | 12 | 3.636364 |
 14 | 30199 | COLLAGEN_FIBRIL_ORGANIZATION | 4.24E-06 | 55 | 100 | 4 | 7.272727 |
 14 | 43062 | EXTRACELLULAR_STRUCTURE_ORGANIZATION | 4.99E-08 | 373 | 100 | 9 | 2.412869 |
High 1–4 day | |||||||
 4 | 44281 | SMALL_MOLECULE_METABOLIC_PROCESS | 1.06E-22 | 1962 | 658 | 83 | 4.230377 |
 4 | 44257 | CELLULAR_PROTEIN_CATABOLIC_PROCESS | 9.84E-23 | 782 | 658 | 52 | 6.649616 |
 4 | 6886 | INTRACELLULAR_PROTEIN_TRANSPORT | 7.04E-29 | 1151 | 658 | 71 | 6.168549 |
 6 | 6629 | LIPID_METABOLIC_PROCESS | 4.53E-13 | 1405 | 355 | 38 | 2.704626 |
 6 | 7049 | CELL_CYCLE | 3.37E-11 | 1864 | 355 | 41 | 2.199571 |
High 3–7 day | |||||||
 16 | 34378 | CHYLOMICRON_ASSEMBLY | 4.54E-07 | 10 | 88 | 3 | 30 |
 16 | 42304 | REGULATION_OF_FATTY_ACID_BIOSYNTHETIC_PROCESS | 1.99E-06 | 56 | 88 | 4 | 7.142857 |
 16 | 46486 | GLYCEROLIPID_METABOLIC_PROCESS | 4.25E-06 | 414 | 88 | 7 | 1.690821 |
 18 | 6887 | EXOCYTOSIS | 2.29E-06 | 900 | 69 | 10 | 1.111111 |
 18 | 8047 | ENZYME_ACTIVATOR_ACTIVITY | 2.56E-05 | 520 | 69 | 7 | 1.346154 |
 18 | 46903 | SECRETION | 1.87E-05 | 1680 | 69 | 12 | 0.714286 |
High 7Â day | |||||||
 5 | 30030 | CELL_PROJECTION_ORGANIZATION | 3.09E-29 | 1545 | 491 | 72 | 4.660194 |
 5 | 45595 | REGULATION_OF_CELL_DIFFERENTIATION | 2.03E-23 | 1881 | 491 | 71 | 3.774588 |
 5 | 35295 | TUBE_DEVELOPMENT | 4.70E-18 | 1122 | 491 | 48 | 4.278075 |
 5 | 22008 | NEUROGENESIS | 1.95E-29 | 1625 | 491 | 74 | 4.553846 |
 7 | 31012 | EXTRACELLULAR_MATRIX | 1.55E-17 | 531 | 320 | 28 | 5.27307 |
 7 | 48870 | CELL_MOTILITY | 1.75E-13 | 1758 | 320 | 42 | 2.389078 |
 7 | 48514 | BLOOD_VESSEL_MORPHOGENESIS | 5.18E-13 | 686 | 320 | 26 | 3.790087 |
 7 | 46695 | REGULATION_OF_CELL_DIFFERENTIATION | 5.59E-14 | 1163 | 320 | 38 | 3.267412 |
 7 | 30030 | CELL_PROJECTION_ORGANIZATION | 5.59E-14 | 1545 | 320 | 40 | 2.588997 |
 7 | 22008 | NEUROGENESIS | 5.12E-16 | 1625 | 320 | 44 | 2.707692 |
 7 | 22610 | BIOLOGICAL_ADHESION | 7.11E-19 | 1425 | 320 | 45 | 3.157895 |
 7 | 1816 | CYTOKINE_PRODUCTION | 3.72E-12 | 808 | 76 | 12 | 1.485149 |
 7 | 2521 | LEUKOCYTE_DIFFERENTIATION | 1.83E-08 | 520 | 76 | 8 | 1.538462 |