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Figure 4 | Veterinary Research

Figure 4

From: Vimentin affects inflammation and neutrophil recruitment in airway epithelium during Streptococcus suis serotype 2 infection

Figure 4

Disruption of vimentin localization inhibits the transcription of cytokines in STEC. A The effect of vimentin inhibitor WFA on the distribution of vimentin (green) in uninfected STEC was examined by immunofluorescence. The cell nuclei were stained with DAPI (blue). Scale bar, 100 μm. STEC pretreated with DMSO or 2.5 μM WFA for 1 h were infected with SS2 (MOI 50) for 2 h, and the transcription of IL-6 (B), TNF-α (C), and IL-8 (D) was determined using RT-qPCR. The same volume of DMSO treatment is the control. Data are representative or are presented as the mean ± SD. **, P < 0.01; ***, P < 0.001.

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