Table 3 KEGG analysis of common DEG in response to 0.05 and 0.25Â mg/mL BP5 immunization
Name | Map | 0.25Â mg/mL BP5 | 0.05Â mg/mL BP5 | Co-Downregulated gene | ||
|---|---|---|---|---|---|---|
Up | Down | Up | Down | |||
Natural killer cell mediated cytotoxicity | map04650 | 1 | 9 | 1 | 10 | Gzmb;Tnf;Klrk1;Klrd1;Prf1;Klre1;Ifng |
Cytokine-cytokine receptor interaction | map04060 | 3 | 11 | 4 | 27 | Ccl4;Tnf;Il18rap;Il1r2;Xcl1;Il1b;Tnfrsf9;Ifng;Il2rb |
Antigen processing and presentation | map04612 | 0 | 8 | 0 | 12 | Tnf;Klrd1;Klre1;Cd8b1;Ifng;Gm9144;Hspa1b |
Hematopoietic cell lineage | map04640 | 1 | 5 | 1 | 11 | Kit;Tnf;Il1r2;Il1b;Cd8b1 |
Complement and coagulation cascades | map04610 | 0 | 6 | 3 | 5 | Plau;C3;Itgax |