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Figure 1 | Veterinary Research

Figure 1

From: Evaluation of immunogenicity and cross-reactive responses of  vaccines prepared from two chimeric serotype O foot-and-mouth disease viruses in pigs and cattle

Figure 1

Schematic diagram of the exchange-cassette cloning strategy described in this study. The FMDV full-length cDNA clone pOFS was used for the construction of two chimeric genome-length cDNA copies. The specific genes (from nt 2924–4183) with the substitution of the VP1 gene of FMDV O/TUR/5/2009 and O/NXYCh/CHA/2018 were synthesized by a biotechnology company.

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Veterinary Research

ISSN: 1297-9716