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Figure 2 | Veterinary Research

Figure 2

From: Duck Tembusu virus infection induces mitochondrial-mediated and death receptor-mediated apoptosis in duck embryo fibroblasts

Figure 2

Caspases are involved in DTMUV-induced apoptosis in DEFs. A Effects of DTMUV on caspases and PARP in infected DEFs. B Changes in DEF viability at 36 h following treatment with Z-VAD-FMK, Z-IETD-FMK and Z-LEHD-FMK. C DEFs were pretreated with inhibitors for 2 h and then infected with DTMUV for 60 h. After incubation, the viruses were collected, and the viral titres were determined. The titres are presented as the Log10TCID50/0.1 mL. D Changes in apoptosis of DEFs induced by DTMUV following treatment with Z-VAD-FMK, Z-IETD-FMK and Z-LEHD-FMK. E Bar graph of the percentage of apoptosis in Panel D; *p < 0.05, ****p < 0.0001.

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