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Figure 4 | Veterinary Research

Figure 4

From: YqeH contributes to avian pathogenic Escherichia coli pathogenicity by regulating motility, biofilm formation, and virulence

Figure 4

Animal systemic infection in vivo. A Determination of bacterial virulence. Seven-day-old chicks were inoculated intratracheally with 108 colony-forming units (CFUs) of APEC40, APEC40-ΔyqeH, or APEC40-CΔyqeH. Chicks that were administered PBS were used as negative control. Survival was monitored for 7 days post-infection. B Bacterial colonization and proliferation in chicks. Groups of eight 7-day-old chicks were intratracheally infected with bacteria (108 CFUs). Bacteria were recovered from the lung, blood, liver, and spleen at 24 h post-infection. The nonparametric Mann–Whitney U-test was used to determine statistical significance (**P < 0.01, ***P < 0.001 for WT vs. mutant).

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