Figure 1

H&E staining to evaluate pathological damage in intestinal tissue. Histopathological sections of the jejunum were collected from mice on Days 3, 7, and 15 post-infection (dpi) (A). Villus length (B) and crypt depth of the jejunum were measured using Image-Pro Plus software. The ratio of villus length/crypt depth is shown in C, and the intestinal pathology score is shown in D. The data are expressed as the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001 compared with the 0 dpi group, ⁺P < 0.05, ⁺⁺P < 0.01, ⁺⁺⁺P < 0.001 compared with the 3 dpi group, ^#P < 0.05, ^##P < 0.01, ^###P < 0.001 compared with the 7 dpi group.