Table 2 Determination of the LD50 of the P. multocida WT and PMZ2 strains
Route | Strains | Challenge dose (CFU) and survival | LD50 (CFU) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
10 | 102 | 103 | 104 | 105 | 106 | 107 | 108 | 109 | |||
Intramuscular | WT | 3/6 | 1/6 | 0/6 | 0/6 | – | – | – | – | – | 14.6 |
PMZ2 | – | – | – | 6/6 | 5/6 | 4/6 | 0/6 | – | – | 1.54 × 106 | |
Oral | WT | – | – | – | 3/6 | 1/6 | 0/6 | 0/6 | – | – | 9.63 × 103 |
PMZ2 | – | – | – | – | – | 6/6 | 6/6 | 6/6 | 6/6 | > 3.05 × 109 | |