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Table 1 Experimental design for study A—homologous vs heterologous protection to a PCV2a Vvaccine

From: A bivalent porcine circovirus type 2 (PCV2), PCV2a-PCV2b, vaccine offers biologically superior protection compared to monovalent PCV2 vaccines

Treatment (T)

Vaccine or Control

n

Vaccination

Challenge

Necropsy

 

Strain

T01

Saline Control

10

Study Day 0 a

2 mL intramuscular in right neck

Study Day 21

2 mL intra-muscular in left neck

2 mL intranasal (1 mL each nare)

PCV2a

Study Day 42

T02

cPCV2a

10

T03

Saline Control

10

PCV2b

T04

cPCV2a

10

  1. a Day of study. Pigs were 20–22 days of age on Study Day 0 which corresponded to the day of vaccination.