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Table 3 List of the main metabolites, SRT and D3-SRT detected in the ovine liver samples with their retention times (tR) from LC–MS and LC-HRMS, m/z of precursor and product ions detected by LC-HRMS, elemental composition and designation

From: Sertraline as a new potential anthelmintic against Haemonchus contortus: toxicity, efficacy, and biotransformation

Compound

Elemental composition

tR

LC–MS

[min]

tR

LC-HRMS [min]

m/z precursor ions [M + H]+

m/z product ions

[M + H]+

Designation

Desmethyl-SRT

C16H15Cl2N

4.73

12.02

292.0648

275.0388

158.9763

129.0702

91.0550

Desm-SRT

SRT

C17H17Cl2N

4.88

12.13

306.0815

275.0382

158.9758

129.0699

91.0548

SRT

SRT-D3 (IS)

C17H17Cl2N

4.88

12.13

309.0991

275.0394

158.9766

129.0699

91.0548

D3-SRT

Desmethyl-SRT-O-glucuronide

C22H21Cl2NO7

6.02

6.27

12.62 1

12.79 2

482.0767

306.0449 1, 2

288.0343 1, 2

253.0654 1, 2

158.9763 1, 2

141.0182 1, 2

Desm-SRT-O-GLU