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Table 3 List of the main metabolites, SRT and D3-SRT detected in the ovine liver samples with their retention times (tR) from LC–MS and LC-HRMS, m/z of precursor and product ions detected by LC-HRMS, elemental composition and designation

From: Sertraline as a new potential anthelmintic against Haemonchus contortus: toxicity, efficacy, and biotransformation

Compound Elemental composition tR
LC–MS
[min]
tR
LC-HRMS [min]
m/z precursor ions [M + H]+ m/z product ions
[M + H]+
Designation
Desmethyl-SRT C16H15Cl2N 4.73 12.02 292.0648 275.0388
158.9763
129.0702
91.0550
Desm-SRT
SRT C17H17Cl2N 4.88 12.13 306.0815 275.0382
158.9758
129.0699
91.0548
SRT
SRT-D3 (IS) C17H17Cl2N 4.88 12.13 309.0991 275.0394
158.9766
129.0699
91.0548
D3-SRT
Desmethyl-SRT-O-glucuronide C22H21Cl2NO7 6.02
6.27
12.62 1
12.79 2
482.0767 306.0449 1, 2
288.0343 1, 2
253.0654 1, 2
158.9763 1, 2
141.0182 1, 2
Desm-SRT-O-GLU