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Table 2 List of the main metabolites, SRT and D3-SRT detected in samples of H. contortus with their retention times (tR) from LC–MS and LC-HRMS, m/z of precursor and product ions detected by LC-HRMS, elemental composition and designation

From: Sertraline as a new potential anthelmintic against Haemonchus contortus: toxicity, efficacy, and biotransformation

Compound Elemental composition tR LC–MS
[min]
tR LC-HRMS [min] m/z precursor ions [M + H]+ m/z product ions
[M + H]+
Designation
Hydroxy-SRT C17H17Cl2NO 3.74
4.04
10.49 1
11.36 2
322.0760 304.0661 2
291.03381
273.0233 1, 2
238.0542 1, 2
SRT-OH
SRT-O-glucoside C23H27Cl2NO6 3.14
3.57
9.54 1
10.65 2
484.1285 273.0232 1, 2
194.1024 1, 2
176.0918 1, 2
SRT-O-GLC
Dihydroxy-SRT C17H17Cl2NO2 3.18
3.34
9.74 1
10.02 2
338.0717 320.0599 1
289.0185 1, 2
261.0230 1, 2
247.0077 1, 2
SRT-2OH
SRT-ketone C16H14Cl2O 3.51 10.48 291.0338 273.0233
238.0543
145.0649
SRT=O
SRT C17H17Cl2N 4.29 12.13 306.0810 275.0387
158.9762
129.0699
91.0548
 
D3-SRT (IS) C17H17Cl2N 4.29 12.13 309.0991 275.0394
158.9766
129.0699
91.0548