Skip to main content

Table 2 Immunization schedule and challenge.

From: Deleting qseC downregulates virulence and promotes cross-protection in Pasteurella multocida

Groups Bacterin (CFU/mL) Primary immune dose (mL) Booster dose (mL) Booster day (dpi) Challenge strain Challenge day (dpi)
Live ΔqseC 4.5 × 107 0.1    PmCQ1, PmCQ2, PmCQ4, PmCQ5, PmB, PmF, PmP, PmQ, and PmR, respectively 21
PBS   0.1    PmCQ1, PmCQ2, PmCQ4, PmCQ5, PmB, PmF, PmP, PmQ, and PmR, respectively 21
Inactivated PmCQ2 5.0 × 109 0.2 0.1 7 PmCQ1, PmCQ2, PmCQ4, PmCQ5, PmB, PmF, PmP, PmQ, and PmR, respectively 21
Inactivated ΔqseC 5.0 × 109 0.2 0.1 7 PmCQ1, PmCQ2, PmCQ4, PmCQ5, PmB, PmF, PmP, PmQ, and PmR, respectively 21
PBS emulsifier   0.2 0.1 7 PmCQ1, PmCQ2, PmCQ4, PmCQ5, PmB, PmF, PmP, PmQ, and PmR, respectively 21
  1. dpi day after primary immunization.