Table 2 Immunization schedule and challenge.
From: Deleting qseC downregulates virulence and promotes cross-protection in Pasteurella multocida
Groups | Bacterin (CFU/mL) | Primary immune dose (mL) | Booster dose (mL) | Booster day (dpi) | Challenge strain | Challenge day (dpi) |
|---|---|---|---|---|---|---|
Live ΔqseC | 4.5 × 107 | 0.1 |  |  | PmCQ1, PmCQ2, PmCQ4, PmCQ5, PmB, PmF, PmP, PmQ, and PmR, respectively | 21 |
PBS | Â | 0.1 | Â | Â | PmCQ1, PmCQ2, PmCQ4, PmCQ5, PmB, PmF, PmP, PmQ, and PmR, respectively | 21 |
Inactivated PmCQ2 | 5.0 × 109 | 0.2 | 0.1 | 7 | PmCQ1, PmCQ2, PmCQ4, PmCQ5, PmB, PmF, PmP, PmQ, and PmR, respectively | 21 |
Inactivated ΔqseC | 5.0 × 109 | 0.2 | 0.1 | 7 | PmCQ1, PmCQ2, PmCQ4, PmCQ5, PmB, PmF, PmP, PmQ, and PmR, respectively | 21 |
PBS emulsifier | Â | 0.2 | 0.1 | 7 | PmCQ1, PmCQ2, PmCQ4, PmCQ5, PmB, PmF, PmP, PmQ, and PmR, respectively | 21 |