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Table 1 KEGG pathways altered in ST416/ST417

From: Genomic signatures of host adaptation in group B Salmonella enterica ST416/ST417 from harbour porpoises

Pathway

Pathway name

Pan-genome

SNP

stm01100

Metabolic pathways

46

30

stm01120

Microbial metabolism in diverse environments

35

9

stm02020

Two-component system

20

9

stm05132

Salmonella infection

13

5

stm02060

Phosphotransferase system (PTS)

12

stm01110

Biosynthesis of secondary metabolites

12

7

stm03070

Bacterial secretion system

12

stm00350

Tyrosine metabolism

10

2

stm00030

Pentose phosphate pathway

9

stm01220

Degradation of aromatic compounds

7

stm01200

Carbon metabolism

6

2

stm02024

Quorum sensing

6

stm02010

ABC transporters

5

5

stm00051

Fructose and mannose metabolism

5

4

stm00520

Amino sugar and nucleotide sugar metabolism

5

4

stm00910

Nitrogen metabolism

5

stm00010

Glycolysis/gluconeogenesis

5

stm01230

Biosynthesis of amino acids

4

stm00310

Lysine degradation

4

3

stm05100

Bacterial invasion of epithelial cells

3

stm00330

Arginine and proline metabolism

3

stm00630

Glyoxylate and dicarboxylate metabolism

3

2

stm00650

Butanoate metabolism

3

2

stm00680

Methane metabolism

3

2

stm00620

Pyruvate metabolism

3

stm00260

Glycine, serine and threonine metabolism

3

stm03430

Mismatch repair

3

stm00760

Nicotinate and nicotinamide metabolism

3

stm00250

Alanine, aspartate and glutamate metabolism

3

stm01503

Cationic antimicrobial peptide (CAMP) resistance

-

3

stm03010

Ribosome

2

stm00071

Fatty acid degradation

2

stm00400

Phenylalanine, tyrosine and tryptophan biosynthesis

2

stm00633

Nitrotoluene degradation

2

stm00640

Propanoate metabolism

2

stm00500

Starch and sucrose metabolism

2

4

stm02030

Bacterial chemotaxis

2

-

stm00564

Glycerophospholipid metabolism

2

stm00562

Inositol phosphate metabolism

2

stm00541

O-Antigen nucleotide sugar biosynthesis

2

stm00540

Lipopolysaccharide biosynthesis

2

stm02060

Phosphotransferase system (PTS)

2

stm00052

Galactose metabolism

2

stm00230

Purine metabolism

2

  1. KEGG pathways significantly enriched for presence/absence variation in isolates of ST416/ST417 compared to the S. enterica type strain LT2 as determined by pan-genome analysis and identification of high impact (i.e., presumed loss of function) SNPs.