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Figure 3 | Veterinary Research

Figure 3

From: Microencapsulated phages show prolonged stability in gastrointestinal environments and high therapeutic efficiency to treat Escherichia coli O157:H7 infection

Figure 3

Therapeutic effects of microencapsulated phages in vivo. A Survival curves of rats within one week after administration of E. coli. Rats challenged with E. coli O157:H7 (109 CFU/mL, 1 mL/100 g) were gavaged with free or microencapsulated phages (108 PFU/rat) 8 h after infection. Rats in the positive control group were gavaged with E. coli O157:H7 and PBS. Rats in the negative control group received only 2 mL of PBS. Survival rates of the rats in all groups were monitored. B Changes in the weights of the rats within one week after administration of E. coli. The weights of the rats in the free phage, microencapsulated phage and negative control groups were monitored for 1 week. Statistical analysis was used to compare the microencapsulated phage group and the free phage group. ns, no significant difference; *P  <  0.05; **P  <  0.01.

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