Ultra- and micro-structural changes of respiratory tracts in SARS-CoV-2 infected Syrian hamsters

Table 2 Reported respiratory lesions on SARS-CoV-2 infected Syrian hamsters

Histopathological parameter		Day post-infection
Histopathological parameter		2	3	4	5	6	7	10
Trachea
Epithelium	Shape change	[25]	[18]		[18]
	Cilia loss	[25]
	Proliferation						[25]
	Necrosis		[18]		[18]
	Inflammatory cell	[25]
	Recover						[25]
	Desquamation	[25]		[25]
Lumen	Exudate
	Hemorrhage
	Inflammatory cell
	Cell debris	[25]
Lamina propria / Submucosa	Inflammatory cell	[25]		[25]
Lamina propria / Submucosa	Edema
Lung
Inflammation		[23, 25]		[25]	[23]
Bronchointerstitial pneumonia		[15]			[15]		[15]
Bronchiole
Epithelium	Shape change			[25]
	Cilia loss
	Proliferation				[15, 24, 27]		[18, 25]
	Necrosis	[22]	[18, 27]		[18]
	Inflammatory cell	[22]	[18, 27]	[25]	[18, 24, 27]
Lumen	Exudate			[25]
	Hemorrhage
	Inflammatory cell	[22]	[27]		[24, 27]
	Cell debris	[22, 25]		[25]
Peribronchiole	Inflammatory cell			[25]	[24]
Alveoli
Epithelium	Proliferation	[22]	[18, 27]	[25]	[18, 24, 27]		[18, 23, 25]
	Necrosis			[25]
	Inflammatory cell		[18, 26]	[26]	[18, 24]	[26]		[26]
Space	Edema	[25]	[18, 26]	[25]	[18]	[26]		[26]
	Inflammatory cell	[25]	[26]	[25]	[18, 24]	[26]		[26]
	Hemorrhage		[26]	[25]		[26]		[26]
Pulmonary Vessel
Perivascular cuffing					[18, 24]			[18]
Congestion/Hyperemia					[24]
Hemorrhage
damage		[22]			[24]

ISSN: 1297-9716