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Figure 8 | Veterinary Research

Figure 8

From: Ultra- and micro-structural changes of respiratory tracts in SARS-CoV-2 infected Syrian hamsters

Figure 8

Ultrastructural features of the alveolar epithelium following infection (n = 3 per group). A The ultrastructure of type 2 pneumocytes. At 8 dpi, the N/C ratio was decreased compared to that in the control, 2 dpi, or 4 dpi. Lamella bodies in the cytoplasm at 8 dpi were remarkable. These lamella bodies were decreased at 16 dpi compared to that at 8 and 12 dpi. H-7650. TEM. 100 kV. Scale bars, 2 μm. B The ultrastructure of type 2 pneumocyte nucleus and adjacent cytoplasm. The nuclear membrane was not clear. It then recovered following the infection period. Lamella bodies observed at 8 dpi were remarkable (black arrow). H-7650. TEM. 100 kV. Scale bars, 0.2 μm. C The ultrastructure of type 1 pneumocyte. The type 1 pneumocyte did not show prominent changes following SARS-CoV-2 infection regardless of infection period. Note that virion-containing vesicles were observed in the cytoplasm at 4 dpi (black arrow). T1, type 1 pneumocyte; T2, type 2 pneumocytes. H-7650. TEM. 100 kV. Scale bars, 0.2 μm.

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