Figure 10

Facilitation or inhibition of larval intrusion by rTsGSCP or anti-rTsGSCP serum. IILl were added to an IEC monolayer, and invaded larvae were examined under a microscope 2 h after cultivation. A The invading larvae were mobile and migratory in the monolayer (the red arrow shows migratory trace); noninvading worms were coiled on the surface of the IECs (B) and C2C12 cells (C). D rTsGSCP accelerated worm intrusion. E Anti-rTsGSCP serum suppressed larval intrusion. F: dsRNA-TsGSCP inhibited larva invasion into IECs. *P < 0.0001 compared to the PBS control groups. Scale bars, 100 μm.